Coach Kyle Whittingham made the announcement Monday after he talked to Wynn and Wynn talked to his father.
Whittingham said Wynn decided it was "time to move on" and that he "fought the good fight" after coming back previously from a pair of season-ending shoulder injuries.
Whittingham said further medical tests need to be done but that it's likely Wynn will need surgery on his left, non-throwing shoulder.
Whittingham said senior Jon Hays and freshman Travis Wilson will battle it out this week for the right to start Saturday's game against No. 25 Brigham Young.
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