The victims were not immediately identified.
The Oregon Transportation Department said debris from the Monday afternoon crash closed state Highway 226 south of Scio until about 8:30 p.m.
KGW-TV reported that the Federal Aviation Administration said the aircraft was an RV-6 single-engine plane. An RV-6 is a 2-seat home-built aircraft constructed from a kit.
The plane crashed in a field in a rural residential area about nine miles east of Albany in the Willamette Valley.
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