With a 24-17 lead at the half, Padron dropped a perfect pass into Kaufman's hands at the goal line. Ronnie Hamlin intercepted ISU quarterback Matt Brown on the next play, setting up Padron's 17-yard strike to Kaufman in the back right corner of the end zone for a 38-17 lead at the 11:01 mark.
The Eagles (11-2), the national champions two seasons ago, host Sam Houston State in a semifinal next weekend.
Padron completed 19 of 33 passes for 358 yards. Kaufman added a clutch 76-yard catch-and-run early in the fourth quarter after the Redbirds (9-4) had scored 18 straight points to close within 38-35. Kaufman finished with nine receptions for 191 yards, becoming the Big Sky Conference record holder for yardage in a season.
Padron's last touchdown, a 10-yarder to Ashton Clark with 7:42 remaining, made it 51-35. Quincy Forte, who rushed for 116 yards on just seven carries, set up the score with a 57-yard burst.
Brown was 27 of 48 for 372 yards but had that that critical interception, plus another in the final seconds. Tyrone Walker had 148 yards receiving and a touchdown on nine catches, and Lechein Neblett caught six passes for 101 yards and a TD. Darrelynn Dunn rushed for 98 yards and a score to go over 1,000 yards for the season.
After Kaufman's back-to-back TDs, ISU came back with a field goal, a 22-yard Brown-to-Neblett score and Brown's 13-yard TD on a quarterback draw. With a two-point conversion, the Redbirds pulled within a field goal with 13:55 to play.
At that point, EWU had run seven plays for minus-21 yards since opening a three-touchdown lead. But on a third-and-9 play, Padron threw the ball up to Kaufman, who ran through a tackle and sprinted down the right sideline to put the Eagles back in control.
The game started out like a track meet, highlighted by a handful of huge plays, before EWU took a 24-17 lead into halftime.
Illinois State opened the game with a long drive that stalled inside the 10, resulting in a Nick Aussieker 23-yard field goal. Eastern Washington responded with Padron's 44-yard scoring pass to Daniel Johnson, who slipped out of the backfield and was wide open down the middle.
The Redbirds answered that with Brown's 40-yard touchdown to Walker. On the ensuing kickoff, EWU freshman Shaquille Hill raced untouched 94 yards for an apparent touchdown, but he dropped the ball at the 2-yard line. The ball bounced into the end zone, but nobody recovered it before a referee touched the ball, resulting in a break for the Eagles -- first and goal at the 1.
ISU held the Eagles to Jimmy Pavel's 20-yard field goal, his school-record 17th this season.
Josh Burch then returned the EWU kickoff 72 yards, setting up Dunn's 3-yard scoring run in the first minute of the second quarter to put the Redbirds up 17-10.
On the following kickoff, Cory Mitchell went 67 yards, setting up a 1-yard run by Demitrius Bronson that tied the game again.
Then there were four straight punts, with the Redbirds getting the ball on the Eastern 46 after the last one. But three plays later, when Brown hit James O'Shaughnessy for 19 yards, T.J. Lee III stripped the ball, which bounced all the way to the Eagles 6, where Jordan Tonani scooped it up and took it to the 21 with 3:21 left.
Padron put together a 12-play, 79-yard drive highlighted by a third-and-17 conversion on a 25-yard pass to Ashton Clark. Zach Gehring capped the drive with a 1-yard TD reception just before halftime.
More Sports Headlines
Seahawks hope to address offense's slow starts Farquhar falters again in M’s 4-2 loss Coca-Cola calls on Blatter to resign Appeals court says lower court must reconsider Solo case Mís notebook: Cano to have sports hernia surgery after season Schmid, Keller to enter National Soccer Hall of Fame together Rain at Dover washes out qualifying; Kenseth on pole Ex-football star Irving Fryar sentenced to 5 years in prison
Our new comment system is not supported in IE 7. Please upgrade your browser here.