Iowa State rallied to beat Tulsa 38-23 on Sept. 1, but the Golden Hurricane put together the comeback in the rematch. Tulsa trailed 17-7 at the end of the first quarter.
The Golden Hurricane (11-3) posted the second 11-win season in school history. Tulsa, which has the smallest enrollment of any Football Bowl Subdivision program, also finished 11-3 in 2008.
Iowa State (6-7) was seeking its second winning season in the last seven years.
Tulsa scored two touchdowns in the first four minutes of the second quarter to pull ahead for good.
Singleton's three scores gave him a school-record 24 touchdown runs this season.
More Sports Headlines
Snohomish mixed martial artist returns to her first love Mariners beat Twins 4-3 in 11 innings Charles scores 29 points, Liberty beat Storm 78-62 Park wins Women's British Open, captures 4th different major Perry wins 2nd straight Champions Tour's 3M Championship Merritt shoots 67 to win Quicken Loans National by 3 shots Triple Crown winner American Pharoah wins $1.75 million Haskell Invitational Bills' Ryan names Incognito starting left guard
Our new comment system is not supported in IE 7. Please upgrade your browser here.