The show is a take on the story of Dr. Jekyll and Mr. Hyde, and stars Steven Pasquale of "Rescue Me." He plays a respected neurosurgeon who turns into a dangerous alter ego each night.
Other cast members include Alana De La Garza and Phylicia Rashad.
"Do No Harm" started with a historically small audience for a major network debut and then dropped further in its second Thursday airing.
NBC will replace "Do No Harm" with reruns of "Law & Order: Special Victims Unit" for the next two weeks.
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