The wolf was killed near Chandalar Lakes about 185 miles north of Fairbanks. The carcass was transported to the Matanuska-Susitna Borough and discarded in a forested area.
The incident has state officials concerned because rabies had not been detected in the area south of the Brooks Range.
They also say the carcass, which has been retrieved, could have spread parasites or the disease.
The wolf had closely approached the trapper.
State officials say people in the Mat-Su or near Chandalar Lakes should report animals acting abnormally.
Wildlife veterinarian Dr. Kimberly Beckmen said rabid animals may be fearless in approaching people, may attack inanimate objects or may move abnormally.
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