On "How I Met Your Mother," it's time for Barney's (Neil Patrick Harris) bachelor party. Of course, it will be legendary as long as Mom (Frances Conroy) and Ralph Macchio don't ruin his "bro mitzvah." 8 p.m., CBS.
On "The Big C: Hereafter," Cathy's (Laura Linney) cancer journey comes to an end with four hourlong episodes beginning tonight. Our advice? Have the tissues handy. 10 p.m., Showtime.
Amanda Knox breaks her silence in a special edition of "20/20" as Diane Sawyer interviews the former American exchange student whose conviction for the 2007 murder of her roommate in Italy was overturned. 10:01 p.m., ABC.
"Manhunt" is a gripping new documentary that chronicles, in great detail, the efforts to track and take down Osama bin Laden. 8 p.m., HBO.
Kal Penn ("House") hosts "The Big Brain Theory: Pure Genius." The competition pits engineers against each other in a series of high-tech challenges, including one that involves explosives. 10 p.m., Discovery.
Is "Scandal" about to get even crazier? In tonight's episode, "some really big stuff" goes down at the White House as an action by the first lady (Bellamy Young) sends Cyrus (Jeff Perry) into crisis-management mode. 10 p.m., ABC.
On "Nikita," our leading lady (Maggie Q) stages yet another daring raid, because, well, daring raids are what they do on this show. 8 p.m., The CW.
"Mr. Hockey: The Gordie Howe Story" recalls NHL icon who ended a brief retirement in 1973 -- at age 45 -- and became the league's only player to suit up in five different decades. 9 p.m., Hallmark Channel.
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