The crash was reported about 4:30 p.m. in the 27700 block of Old Owen Road, Sultan Fire Chief Merlin Halverson said.
A Volkswagen Jetta was side swiped by a full-sized pickup, Halverson said. A young man and a young woman who were in the Jetta were taken via helicopter to Harborview Medical Center in Seattle.
Their injuries appeared life-threatening, the chief said.
The truck driver was taken to the hospital in Monroe.
The Snohomish County Sheriff's Office is investigating. No additional details were immediately available Monday.
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