The collision occurred around 4:15 p.m. about one mile east of Index when a westbound car crossed the centerline and struck a Ford F-250 pickup truck, Washington State Patrol trooper Mark Francis said.
The accident tied up traffic for hours. The road was reopened at about 8:30 p.m.
The driver of the car, a four-door Mercedes, died at the scene. The car reportedly was being driven erratically before the collision, Francis said.
His passenger, a pregnant woman, was taken to a hospital with serious injuries, he said.
Three men in the pickup truck also were taken to hospitals.
Names, ages and hometowns of the people involved in the crash were not immediately available.
More Local News Headlines
Everett City Council puts courthouse deal on hold over parking questions Monroe skatepark will undergo $240,000 worth of improvements GPS coming to most local police, fire vehicles Locals fondly recall author Ann Rule Man sought in Marysville shooting Voters to decide on Marysville fireworks ban Life in prison for killer of Seattle police officer who was from Marysville Volunteer brings troubled felines to inmates, who help tame them
Our new comment system is not supported in IE 7. Please upgrade your browser here.