Sizemore, a graduate of Cascade High School in Everett, returned to the major leagues this season after injuries sidelined him between from September 2011 until this season. He made the American League All-Star team three times with the Cleveland Indians, but has undergone seven operations since 2009, including surgery on both knees, his back and elbow.
Sizemore hit .333 in spring training and started in center field on opening day when he homered in Boston's 2-1 loss at Baltimore. But in 52 games, he hit .216 with two homers and 15 RBI.
By designating Sizemore for assignnent, Boston removes him from the 25-man major-league roster and has 10 days to either trade or release him.
To replace Sizemore on the roster, the Red Sox recalled third baseman Garin Cecchini From Class AAA Pawtucket. He played one game with Boston, on June 1, going 1-for-2 with an RBI double in a 4-0 win over Tampa Bay.
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