First ancient African genome reveals complex migrations

Africa is considered to be the birthplace of humankind. But because its climate is poorly suited for DNA preservation, all of the ancient genomes to be analyzed have been from Europe, Asia, and the Americas. That changed Thursday, when researchers published a paper in Science documenting the genetic code of a man who died 4,500 years ago in what’s now Ethiopia.

Scientists know that after the great migration from Africa — treks that took place about 60,000 years ago — some of the Eurasians who developed agriculture made their way back into Africa.

That’s what makes the newly sequenced man, named Mota, so interesting. Mota lived in Africa before this second, backwards migration. He lacked the Eurasian DNA that seems to have proliferated across the region about 1,500 years after his death.

By comparing his DNA to that of modern Africans, scientists were able to estimate how large the Eurasian influx had been.

“Roughly speaking, the wave of West Eurasian migration back into the Horn of Africa could have been as much as 30% of the population that already lived there — and that, to me, is mind-blowing. The question is: what got them moving all of a sudden?” said Andrea Manica, an author of the study from the University of Cambridge.

Today, Manica said, East Africans can attribute as much as 25 percent of their DNA to this Eurasian back flow. Even in western and southern areas, at least 5 percent of the genome is Eurasian.

The authors have no idea what caused such a big migration. But as techniques for analyzing the ancient DNA of Africa improve, we’ll have more and more studies like this one to fill in the gaps of humanity’s origin story.

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