Top 5 Best Joint Supplements for Women (2024 Update)

  • Wednesday, December 27, 2023 4:29pm
  • Blog

Joint health is crucial for women of all ages. Whether you are an athlete, a fitness enthusiast, or want to maintain your mobility and overall well-being, finding the right joint support supplement is essential. With so many available options, choosing the best one for your needs can be overwhelming.

Why Joint Health Matters for Women

Women are more prone to joint issues due to various factors such as hormonal changes, pregnancy, menopause, and the physiological differences between men and women. Additionally, women tend to have smaller joints and less muscle mass, which can put extra pressure on the joints and increase the risk of injuries and discomfort. Maintaining optimal joint health is crucial for women to enjoy an active lifestyle and prevent pain and mobility limitations.

Top Joint Support Supplements for Women

  • FlexAgain – Best Overall Joint Pain Relief Supplement
  • EstroCare – Best Joint Supplement for Women During Menopause
  • Elm & Rye – Best Turmeric Supplements
  • Elm & Rye Fish oil – Best Omega 3 Fish oil
  • Osteo Bi-Flex – Best Budget Glucosamine Supplements

After extensive research and analysis, we have compiled a list of the top joint support supplements for women. These supplements have been chosen based on their ingredient profiles, manufacturer reputation, customer reviews, personal experiences, and the overall effectiveness of each product. Here’s the full breakdown of our recommendations:



FlexAgain is the most comprehensive joint support supplement, and while it isn’t specifically formulated for women, it is still the best joint supplement on the market, hands down. This means that, in this case, it is the best for everyone, whether managing arthritis pain or looking for general joint supplements to help you stay active or recover from an injury. It’s almost always the right choice.

It contains a blend of scientifically proven ingredients recommended by the arthritis foundation, such as Omega 3, Glucosamine, chondroitin, MSM, and Curcumin (the extract from Turmeric), in total 11 known joint pain relief supplements all rolled into one.

This also includes many of the recommended vitamins and minerals required to promote joint health and mobility, including lesser-known ones like vitamin k2 and common deficiencies like vitamin D. FA Nutra, the manufacturer of FlexAgain, has a strong reputation, both in the US and UK for producing high-quality supplements.

And their customer reviews are overwhelmingly positive, which isn’t too much of a surprise when they seem to honor their money-back guarantees with no questions asked.

FlexAgain does not contain any proprietary blends, unlike many of its competitors in the joint supplements space, meaning that it lists all its ingredients and dosages on the bottle for total transparency.

Except for some of the specific ingredients in EstroCare, which are explicitly targeted at menopausal joint issues, it has pretty much every element in all of the other supplements on this list combined, and without costing much more than any of them, if at all. FlexAgain offers a tremendous all-in-one joint supplement for women seeking to alleviate joint pain.


  • FlexAgain has excellent reviews on third-party sites such as Trustpilot and Reddit and their website.
  • Premium products.
  • The latest scientific research backs it.
  • NO proprietary blend.


  • Only available from the leading website

EstroCare By Nutra FA


EstroCare is recommended for joint pain relief during the Perimenopausal, Menopausal, and Postmenopausal symptoms. This is a natural part of life, but we all know some side effects of this time can negatively affect women’s quality of life.

Joint issues can become even more apparent, leading to long-term problems, most commonly knee osteoarthritis and osteoporosis.

EstroCare contains all the essential vitamins and minerals to help deal with joint and cartilage breakdown and other menopausal issues. In designing this supplement, EstroCare has blended a product based on the most well-studied and scientifically proven ingredients that can help manage symptoms.

We gave this product our top performer when dealing with hot flashes, mood swings, and joint pain relief in a separate review of the best supplements of its type and being well-rated for sleep. But they also have a host of ingredients for joints. While not solely designed for this, Estrocare contains powerful anti-inflammatory ingredients from ginseng and Siberian rhubarb right through to DHEA, which helps prevent bone breakdown that causes osteoporosis.

Everything is in its ideal dosage as studied at clinical trials; we highly recommend Estrocare for women over 50.


  • EstroCare has excellent reviews
  • Premium ingredients
  • NO proprietary blend.


  • It only recently launched in the US, so stock is limited

Elm & Rye Turmeric


Turmeric is a popular joint support supplement that has gained recognition for its efficacy in alleviating joint pain and improving mobility. It contains a unique blend of natural ingredients, including Turmeric and Curcumin. The manufacturer follows strict quality control measures and has received certifications from reputable organizations.

Turmeric is a spice that comes from the turmeric plant. It is commonly used in Asian food. Turmeric has been known to help reduce inflammation, improve joint pain, and is a natural antioxidant.

Curcumin is the main active ingredient in Turmeric. It has powerful anti-inflammatory effects. Inflammation is a natural process that helps your body heal and defend itself from harm. However, inflammation is harmful if it becomes chronic. Chronic inflammation may last for weeks, months, or years. This chronic inflammation, in turn, may lead to various additional health problems. Curcumin has powerful antioxidant effects. It neutralizes free radicals on its own but also stimulates your body’s antioxidant enzymes.


  • Turmeric By Elm & Rye has excellent reviews on Amazon and their website; most are very positive.
  • Premium ingredients.
  • NO proprietary blend.


  • This is a premium brand and may seem expensive.

Elm & Rye Fish Oil


Omega-3 is one of the most commonly used joint supplements worldwide. Omega 3’s are a family of essential fatty acids necessary to your body and have been scientifically proven to provide critical structural benefits to eyes, joints, and numerous other body parts.

Omega-3 can be found in everyday foods such as fatty fish, fish oils, chia seeds, walnuts, and more. For people who don’t often eat foods that are high in omega-3, it is recommended that they take some supplements.

Omega-3 produces signaling molecules called eicosanoids, which have various roles related to joint inflammation, eye health, heart health, and blood clotting, with many more clinical studies reviewing additional benefits.


  • Helps reduces inflammation
  • Scientifically proven to support muscle and joint health
  • Made with high-quality ingredients.
  • Only uses sustainable ingredients,
  • Lab tested to ensure potency and quality
  • Elm & Rye Fish Oil supplement contains 1000 mg of high-quality fish oil per serving.
  • Great for daily aches and pains, especially after a good workout.


  • For severe joint pain such as that caused by Osteoarthritis, this is not as good as FlexAgain.

Osteo Bi-Flex Triple Strength + Vitamin D


From one of America’s most well-known joint supplements, we’ve picked out the best option from their range of glucosamine supplements. Osteo Bi-Flex Triple Strength + Vitamin D claims to be the only glucosamine-based joint supplement made with Joint Shield 5-LOXIN Advanced, which, in effect, is Boswellia Serrata extract, which is, of course, a little bit less unique sounding and no longer so revolutionary.

However, Boswellia is still a solid ingredient that is scientifically proven to be a potent anti-inflammatory. It provides 1500 mg of Glucosamine to help nourish and strengthen your joints long-term and Vitamin D to support strong bones and a healthy immune system. The most exciting thing about Vitamin D as an ingredient is that a deficiency can cause joint problems. And most importantly, it’s pretty cheap, making it a solid budget option.


  • Excellently dosed glucosamine supplement.
  • NO proprietary blend.


  • Mixed reviews, mostly positive.
  • Limited ingredients.

Other Popular Joint Supplements For Women

This is the section where we cover some of the most popular supplements for women’s joints; there’s a reason that a lot of these didn’t make our list: some of them just aren’t very good, but others are beaten out by better options in their price range or category.

  • Relief Factor
  • Move Free Advanced Plus MSM By Schiff
  • Doctor’s Best Hyaluronic Acid with Chondroitin Sulfate
  • ALFLEXIL Glucosamine Chondroitin Cream with MSM + Collagen
  • Heal-n-SOOTHE by Living Well Nutraceuticals

Relief Factor


Relief Factor is a powerful, 100% drug-free botanical and fish oil research-based formula created to help support your body’s inflammatory response.

Epimedium (Aerial) (Standardized to 20% Icariin) Studies have also shown that it may be effective in increasing bone density and reducing joint inflammation while boosting blood flow.

Turmeric: It is commonly used in Asian food. Turmeric is a natural anti-inflammatory agent and antioxidant that can alleviate joint pain.

Japanese Fleeceflower (Root) (Standardized to 96% Resveratrol) Has traditionally been widely used in Chinese medicine; you may also see this labeled Japanese Knotweed. Some studies have shown that regular use of resveratrol can reduce inflammation and improve joint blood flow. What is well less understood is whether the amount of this active ingredient contained in the Relief Factor would significantly affect the joints. However, it’s a little underdosed in the relief factor, and FlexAgain is a better option.


  • Contains clinically tested ingredients
  • All-natural formula


  • More expensive than comparable brands
  • It doesn’t contain Glucosamine
  • Only unopened products are accepted for refund
  • Steep price point.
  • It is only available on the company’s website.
  • Fish oils are not suitable for veterinarians.

Move Free Advanced Plus MSM By Schiff


Move Free Advanced Plus MSM, in our opinion, is a relatively decent joint health supplement. It contains essential joint-care nutrients such as Glucosamine and chondroitin, which claim to support your joints over the long term. However, when looking at customer reviews, in our opinion, this falls into the category of a middle-of-the-road product. At the same time, there are no negative reviews, and all the reviews are pretty positive, but most are only 3-star reviews. Move Free Advanced is manufactured by Schiff, whose parent company, Reckitt Benckiser, is the maker of Veet, Lysol, and Strepsils. So we know that we’re looking at a well-established brand.


  • Contains clinically tested ingredients
  • Move Free Advanced Plus MSM uses a form of Glucosamine that may provide a higher compound concentration in the formula.


  • More expensive than comparable brands
  • The formula misses out on antioxidants, which may help improve joint protection from future damage and aging.
  • When compared with FlexAgain, the inflammatory components are limited, which may result in slower relief from joint swelling and pain.
  • Fish oils are not suitable for veterinarians.
  • Not Suitable for vegans and vegetarians.
  • It uses a proprietary blend, which is not ideal.

Doctor’s Best Hyaluronic Acid with Chondroitin Sulfate


Doctor’s Best Hyaluronic Acid with Chondroitin Sulfate is a joint health supplement that contains BioCell Collagen, Hyaluronic Acid, Chondroitin Sulfate, and Glucosamine. According to the manufacturers, BioCell Collagen is a patented dietary ingredient that contains naturally occurring hydrolyzed collagen type II, chondroitin sulfate, and hyaluronic acid in a highly absorbable matrix. Hyaluronic acid is crucial for skin and joint health. Chondroitin sulfate and Glucosamine enhance joint lubrication and water retention.

So, what is hydrolyzed collagen type II? The Collagen found in supplements can be extracted from several animal sources, including cows and pigs.

Recent research has shown good properties of HC in the skin, scales, and bones of marine sources, such as fish, and invertebrates, such as shellfish, jellyfish, or sponges. Some manufacturers also extract Collagen from algae, and in Doctors’ best, this is extracted from a Vegan source.

Does hydrolyzed collagen type II work? In a study of 250 subjects with knee osteoarthritis, participants were given 10 grams of hydrolyzed Collagen daily for six months. Results showed that there was a significant improvement in knee joint comfort. Interestingly, those with the most critical joint deterioration benefited the most. The problem is that there is nowhere near as much of said Collagen here.


  • Contains clinically tested ingredients
  • Vegan suitable
  • Positive reviews


  • Based on scientific evidence, 10 mg is required daily to benefit from hydrolyzed Collagen fully. This leaves this product considerably under-dosed.
  • Currently, it is only available on the manufacturer’s website.

ALFLEXIL Glucosamine Chondroitin Cream with MSM + Collagen


Alflexil Glucosamine & Chondroitin Cream with MSM & Collagen is a natural cream that contains Glucosamine, chondroitin, MSM, and Collagen. It is designed to soothe joint, bone, and muscle pains, improve mobility, relieve discomfort, and speed healing. It’s pretty good and is not in the best joint supplements section because we’re unsure whether we should classify it as a supplement.

Alflexil claims that its product, containing Glucosamine, chondroitin, MSM, and Collagen, can be applied to areas of joint pain to ease soreness and relieve pain. Alflexil claims that it supports the elasticity in the joints and its cushioning properties, as well as keeps skin soft and moisturized. MSM is an organic source of sulfur, vital in nutrition to maintain the health of cells and connective tissue.


  • Contains clinically tested ingredients
  • Positive reviews are minimal.
  • It aims to soothe joint pain.
  • Currently available on Amazon.


  • Only a small number of reviews are available.
  • It does not offer the same level of pain long-term pain relief that may be found using other products listed within this review.

Heal-n-SOOTHE by Living Well Nutraceuticals


Heal-n-SOOTHE is an anti-inflammatory dietary supplement that claims to be “Mother Nature’s Feel Good Formula.” It boasts its effectiveness in relieving pain—Heal-n-SOOTHE, produced by Living Well Nutraceuticals. Heal-n-Soothe is marketed as a natural pain relief supplement. The brand claims that the critical ingredients in Heal-n-SOOTHE have been proven effective in numerous clinical studies to relieve joint pain and ease joint mobility.

Unfortunately, while this is true, most of the ingredients were scientifically tested with much higher doses than that used in Heal and Soothe. We feel, especially at this price range, FlexAgain is a better option as it offers correctly dosed ingredients and more proven ingredients, all for roughly the same price. However, some of us still found that these gave us assistance and pain relief.


  • It contains some research-backed ingredients for pain relief
  • No questionable additive ingredients
  • Free trial available through the brand’s website


  • Some active ingredients may be under-dosed
  • Potential blood-thinning effect
  • Mixed user reviews on Amazon
  • Protease may increase pain.

Factors to Consider When Choosing Joint Support Supplements

Several key factors must be considered when selecting the right joint support supplement. By evaluating these factors, you can make an informed decision and choose a supplement that will effectively support your joint health and overall well-being.

Best Ingredients for Joint Supplements

The ingredient list is the first thing you should check when evaluating a joint support supplement. Look for supplements that contain safe and effective ingredients known for their joint health benefits. Unfortunately, lots of manufacturers considerably under-dose their products. Dosages should be included as recommended by Arthritis and joint pain institutions worldwide. This review has not included manufacturers we believe have underdosed ingredients and fail to offer value for money.

Some key ingredients to look for include (see below). At the same time, this list is not considered finite, as there are many effective ingredients, many of which are still undergoing scientific trials.

However, based on current scientific research data and customer recommendations, the ingredients listed below are the most effective in dealing with joint pain and mobility.

Omega 3 – Most of us know that we need Omega 3 to keep joints healthy,

Vitamin D deficiency exacerbates joint pain

Vitamin K2 – Current studies show that getting enough vitamin K can slow the progression of Osteoarthritis symptoms.

Ginger and Blue Galangal Extract – Ginger is well documented as a potent natural anti-inflammatory and, as a result, great for joint pain relief—Bromelain is not the best-known joint aid supplement. However, recent studies have proven to be very promising.

Curcumin extract – This compound comes from Turmeric. It’s known to be a potent anti-inflammatory.

Resveratrol – Resveratrol has been proven to be a potent anti-inflammatory and has been shown to have a multitude of other health benefits.

Boswellic Acid – Boswellic Acids are known anti-inflammatories.

Glucosamine – This compound is a building block of cartilage and can help support joint structure and function. It’s been suggested that chondroitin and Glucosamine can potentially alleviate joint pain. Studies believe this may delay cartilage breakdown, relieve osteoarthritis pain, and make your joints more mobile.

Chondroitin – Chondroitin supplements are often paired with Glucosamine, as research suggests it’s effective in enhancing its ability to reduce inflammation and support the production of healthy cartilage.

MSM – MSM (Methylsulfonylmethane) is a sulfur compound that can help reduce joint pain and inflammation.

Collagen – Collagen is a protein that maintains joint and connective tissue integrity.

Hyaluronic Acid – Hyaluronic acid helps lubricate the joints and improve joint mobility.

Ensure that the supplement you choose contains these essential components appropriately, as qualified health professionals recommend.

Manufacturer Reputation

Researching the joint support supplement manufacturer is crucial to purchasing a high-quality product. Look for companies with a good reputation for producing reliable and effective supplements. Consider the following factors when evaluating the manufacturer:


When selecting a supplement for joint support, it is essential to consider the formulation as it dramatically affects effectiveness. Different companies may offer various combinations of ingredients. We recommend you look for supplements that provide a comprehensive blend of joint-supporting ingredients. We always try to avoid supplements that include proprietary blends as these do not list the dosages for each component; this, in turn, makes it impossible to determine the blend’s effectiveness.


Check the recommended dosage of the joint support supplement and ensure it is suitable for your age, weight, gender, and medical history. It’s crucial to follow the instructions provided by the manufacturer. If you have any specific health concerns or are taking other medications, consult your doctor or pharmacist to determine the appropriate dosage.


Third-party certifications are essential indicators of the quality control measures taken by supplement manufacturers.

Side Effects

Before purchasing a joint support supplement, one must be aware of potential side effects. Review feedback from other users to determine if there are any reported side effects associated with the supplement.


Reading reviews from other people who have used the joint support supplement can provide valuable insights into its effectiveness and any potential issues.

Refund Policy

Check if the company offers a refund policy or a money-back guarantee. A firm refund policy indicates the company’s confidence in its product.

Additional Considerations

In addition to the factors mentioned above, there are a few other considerations to keep in mind when selecting a joint support supplement:

Allergens: If you have any known allergies, check the supplement’s ingredient list to ensure it does not contain any allergens that may trigger a reaction.

Interactions with Medications: If you take any medications, consult your healthcare provider to ensure the joint support supplement will not interact negatively with your current medicines.

Top Joint Support Supplements for Women Conclusion

Maintaining optimal joint health is crucial for women to lead an active, pain-free lifestyle. When choosing a joint support supplement, consider factors such as the ingredient list, manufacturer reputation, cost, formulation, dosage, certification, side effects, reviews, and refund policy. You can select the best joint support supplement for your needs by evaluating these factors and conducting thorough research.

When we looked at the above factors, we had no hesitation in recommending FlexAgain as our number one overall Joint supplement. This brand has scientifically proven premium ingredients, dosed at the correct levels recommended by health organizations worldwide.

Remember to consult with your healthcare provider before starting any new supplement regimen. Support your joint health for mobility and well-being with a top joint supplement above.


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