Most doses of vaccine are made in a production process that involves growing viruses in chicken eggs. (AP Photo/David Goldman)

Most doses of vaccine are made in a production process that involves growing viruses in chicken eggs. (AP Photo/David Goldman)

Flu shot only 36 percent effective, making bad year worse

Experts wonder if low vaccine effectiveness is another reason for the surprisingly severe season.

  • By MIKE STOBBE AP Medical Writer
  • Thursday, February 15, 2018 11:21am
  • Nation-World

By Mike Stobbe / Associated Press

NEW YORK — The flu vaccine is doing a poor job protecting older Americans and others against the bug that’s causing most illnesses.

Preliminary figures released Thursday suggest the vaccine is 36 percent effective overall in preventing flu illness severe enough to send a patient to the doctor’s office.

There’s only been one other time in the last decade when the flu vaccine did a worse job.

Most illnesses this winter have been caused by a nasty kind of flu called Type A H3N2. The vaccine was only 25 percent effective against that type.

This kind of virus tends to cause more suffering and have been responsible for the worst recent flu seasons. But experts have wondered whether low vaccine effectiveness is another reason for the surprisingly severe season hitting the United States this winter.

Based on these numbers, the answer is yes.

“The fact that the vaccine doesn’t work as well as we would like is clearly a contributing factor,” said Dr. William Schaffner, a Vanderbilt University vaccine expert.

The vaccine was somewhat effective in young children, but it was nearly ineffective for older people, including seniors who are most vulnerable. The estimates were published by the Centers for Disease Control and Prevention.

The numbers are a snapshot taken in the middle of a frantic flu season. They are based on relatively small numbers of people and they are considered preliminary. Numbers may change as the season continues and more patients are added to the study.

And experts say it’s still worth getting a flu shot. It still provides some protection, it can lessen the illness’s severity, keep people out of the hospital, and save lives. There are as many as 56,000 deaths connected to the flu during a bad year.

“Any type of vaccine is better than none,” said Scott Hensley, a University of Pennsylvania microbiologist who has led studies that raised critical questions about the vaccine.

The effectiveness estimates come from the tracking of about 4,600 children and adult patients in five states. To make the effectiveness calculations, researchers tracked who got the flu, and who among them had been vaccinated.

The vaccine provided good protection — 67 percent effective — against another common kind of flu virus, Type A H1N1, which has not been seen much this winter. And it was 42 percent effective against Type B flu viruses.

Hensley and some other researchers say part of the problem is tied to how 85 percent of the nation’s flu vaccine doses are made. Manufacturers grow flu viruses in chicken eggs. But the viruses can mutate in the eggs, and what emerges for use in the vaccine is less effective in people.

The problem seems to be specific to H3N2 viruses, Hensley said.

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