A good joint pain supplement can change your life.
Joint pain supplements use natural ingredients to support pain relief and boost mobility. Using the right combination of vitamins, minerals, herbs, and plant extracts, you could enjoy rapid joint pain relief.
Some joint pain supplements are better than others.
Some joint pain supplements use science-backed ingredients to rapidly relieve joint pain. Other supplements use unproven ingredients with weak dosages.
When you take a joint pain supplement, you expect it to work quickly to relieve joint pain. Our editorial team contacted manufacturers, checked lab research, and tested the world’s leading joint pain and mobility supplements. Here are our rankings.
Ranking the Best Joint Health Supplements for Pain Relief in 2021
Based on our proprietary ranking formula, here are the best joint pain supplements available today.
- BioTRUST Joint 33X
- PureHealth Research Joint Support
- PhytAge Labs Joint Relief 911
- Zenith Labs Joint N-11
- ProJoint Plus
- 1MD MoveMD
- Nuzena Joint Support +
- Thrive Health Labs Joint Guard 360
- Onnit Joint Oil
- UpWellness Golden Revive +
- Zenith Labs Longevity Activator
- Cymbiotika Ultimate Pain Balm
- Oweli Move Joint Health Formula
- Live Conscious Movewell+
- Prosper CBD Joint Restore Gummies
- CBDPure CBD Infused Cream
- Advanced Bionutritionals Advanced Joint Support
- Nature Heals Proflexoral
- 3 Naturals Triple Joint Health
- Healthy Back Institute Super Joint Support
- CellGrail Maximum Flex
- NSP Nutrition Ultra Joint Relief Pro
- MindBody Matrix Pain Relief Cream
- Nutrition Hacks Joint Pain Hack
- Move Free Joint Health
- Vimerson Health Glucosamine Chondroitin Turmeric & MSM
- Jocko Joint Warfare
People experience joint pain for different reasons, which is why some people experience rapid relief from some joint pain supplement ingredients but not others. That’s why BioTRUST added three separate joint pain ingredients to its Joint 33X formula. The 3-in-1 joint pain supplement aims to provide advanced relief to people experiencing all types of joint pain.
According to BioTRUST, people who take Joint 33X daily could support joint health, joint flexibility, joint function, and overall comfort, among other benefits.
To provide those benefits, Joint 33X contains Mobilee extract (which is rich with hyaluronic acid and collagen), UC-II (type II undenatured collagen), and ApresFlex (a type of Boswellia serrata extract). These three ingredients work in different ways to support joint pain relief from multiple angles. Plus, all purchases are backed by a 60 day moneyback guarantee.
PureHealth Research Joint Support
Joint Support from PureHealth Research is one of the supplements on our list that was formulated by a doctor. Made by Dr. Holly Lucille, ND, Joint Support is a joint pain supplement backed by a longer guarantee than virtually any other formula on this list. You have 365 days to try the formula and decide if you like it.
Like other top-ranked joint pain relief supplements on our list, Joint Support contains a blend of multiple ingredients instead of a single ingredient. Each serving of PureHealth Research Joint support contains turmeric, resveratrol, Boswellia serrata, type II collagen, hyaluronic acid, and omega-3 fatty acids. PureHealth Research has even added black pepper extract (Bioperine), an ingredient shown to boost the absorption of turmeric.
According to Dr. Lucille and the PureHealth Research team, people who take Joint Support could enjoy natural support for healthy joints and cartilage, nourishment to repair joints and cartilage, healthy immunity markers, healthy joint flexibility and mobility, and an overall feeling of younger joints, among other benefits.
PhytAge Labs Joint Relief 911
Joint Relief 911 from PhytAge Labs is a joint pain supplement that uses just two active ingredients to support joint pain relief. Each two capsule serving of Joint Relief 911 contains 250mg of Andrographis paniculata (in a 4:1 concentration) and 30mg of hyaluronic acid.
According to PhytAge Labs, Andrographis paniculata has powerful antioxidant and anti-inflammatory properties that make it effective for joint relief. Meanwhile, hyaluronic acid is crucial for lubricating your joints and retaining moisture.
If you haven’t experienced joint pain relief with other supplements on this list, then Joint Relief 911 may be a good alternative. It uses unique ingredients compared to competing formulas, and many experience relief thanks to these alternative ingredients.
Zenith Labs Joint N-11
Joint N-11 is a joint pain supplement that, like other top-rated joint supplements on our list, was formulated by a doctor. According to Zenith Labs and its medical advisory board, Joint N-11 can support your body in protecting joint cartilage, giving you easy movement. The supplement also claims to support hand and wrist health for daily tasks while also supporting your knees, backs, and hips for maximum mobility.
Joint N-11 is designed to target the two most common causes of joint pain: decaying cartilage in your joints and inflammation within your joint tissue. Each two capsule serving of Joint N-11 contains 10 active ingredients, including niacin, turmeric, ginger root powder, MSM, N-acetyl L-cysteine, frankincense, basil leaf powder, rosemary leaf powder, soy lecithin, and black pepper extract. Just take two capsules daily for joint pain relief.
Like other Zenith Labs supplements, Joint N-11 was created by primary researcher, formulator, and Chief Medical Officer Dr. Ryan Shelton, NMD. Using his experience in natural medicine, Dr. Shelton created Joint N-11 to address common causes of joint pain.
ProJoint Plus is a natural nutritional supplement designed to support cartilage health, support joint health, and support natural joint mobility. Each three capsule serving of ProJoint Plus contains a 1,500mg dose of glucosamine sulfate, which is one of the most popular and proven ingredients for joint pain relief.
Other key ingredients in the formula include Boswellia serrata extract (200mg), chondroitin sulfate (150mg), and turmeric (150mg). If you want a glucosamine sulfate supplement with added power and effectiveness, then ProJoint Plus may be the right choice.
Another advantage of ProJoint Plus is the price. At $30 per bottle, it’s one of the more cost-effective options on our list. However, please note that each 60 capsule bottle lasts just 20 days – not the 30 day supply we get with other joint pain supplements.
1MD’s MoveMD is a joint pain supplement that claims to reduce joint discomfort in as few as 5 days. Like certain other joint pain supplements on this list, MoveMD contains ApresFlex, a Boswellia extract formula designed to relieve joint pain in multiple ways.
Other key ingredients in MoveMD include Zanthin, a natural type of astaxanthin formula. Astaxanthin appears to have antioxidant benefits, which could help your body control inflammation in various ways.
By taking MoveMD daily, 1MD claims you can reduce joint discomfort, promote joint mobility and flexibility, help maintain connective tissue, and reduce oxidative stress for less stiffness and soreness, among other benefits. All purchases are backed by a 90 day moneyback guarantee.
Nuzena Joint Support +
Nuzena’s Joint Support + is a joint health support formula with glucosamine and chondroitin, two of the most popular and proven ingredients for joint health.
Priced at $35 per bottle, Joint Support + claims to provide natural support for joint health and mobility while acting as a natural anti-inflammatory and offering natural support for healthy bones and cartilage.
To provide these benefits, Joint Support + contains ingredients like glucosamine, turmeric, chondroitin, quercetin, bromelain, and Boswellia serrata extract, all of which are among the most popular and proven joint pain ingredients available today. Plus, with a 1,500mg dose of glucosamine sulfate and strong doses of other ingredients, Joint Support + gives you strong value compared to other joint supplements.
Thrive Health Labs Joint Guard 360
Joint Guard 360 from Thrive Health Labs is an advanced joint health formula that contains strong doses of turmeric, glucosamine, and ginger extract along with smaller doses of quercetin, bromelain, and MSM.
Each two capsule serving of Joint Guard 360 contains 800mg of turmeric root and an additional 100mg of turmeric with a 95% concentration, allowing you to maximize the curcumin that enters your body. Curcumin is the active ingredient in turmeric, and it could help your body manage inflammation. Joint Guard 360 also contains black pepper extract (Bioperine), which has been shown to boost the absorption of turmeric by 2,000%.
If you want a turmeric joint pain relief supplement with additional effects, then Thrive Health Labs’ Joint Guard 360 may be the right choice for you.
Onnit Joint Oil
Joint Oil is a tangerine-flavored omega-3 fatty acid supplement that targets joint pain, mobility, and health in a different way than other formulas on our list. While other formulas target inflammation and cartilage using anti-inflammatory herbs, Joint Oil combines omega-3s from fish oil, GLA from borage oil, curcumin from turmeric, and unsaponifiable oils – four ingredients proven to support joint health.
Onnit’s Joint Oil is also one of the few supplements on this list with its own flavor. While you swallow or chew other joint pain supplements on this list, you drink Onnit’s Joint Oil daily to support joint health.
Each two teaspoon (10mL) serving of Onnit Joint Oil contains significant doses of fish oil, borage seed oil, and avocado oil, among other ingredients. You get 1.6g of fish oil with 160mg of EPA and 130mg of DHA in each serving, for example, along with 160mg of GLA from borage seed oil. If you believe in the power of natural oils to support joint pain and inflammation, then Onnit’s Joint Oil is one of the best options available. Like other Onnit supplements, it’s also backed by more scientific evidence – and made with a higher standard of quality – than most other joint supplements on this list.
UpWellness Golden Revive +
UpWellness’s Golden Revive + is an advanced, physician-formulated supplement to help you move freely again. By taking Golden Revive + daily, you can purportedly promote an improved range of motion, reduce scarring and tissue damage, support healthy joints, improve circulation, and promote healthy cholesterol levels, among other benefits.
In other words, Golden Revive + will do more than just support joint health; it will also support overall health from your heart out. To provide all of these benefits, Golden Revive + contains curcumin, Boswellia serrata, bromelain, quercetin, magnesium, and piperine. In fact, UpWellness claims Golden Revive + is 200x more powerful than raw turmeric powder because the supplement contains a proprietary form of curcumin (BCM-95 curcumin) for maximum absorption.
Zenith Labs Longevity Activator
Longevity Activator was created with the idea that aging is a choice – not a life sentence. Although that claim may be a bit dramatic, Longevity Accelerator uses unique natural ingredients to support anti-aging defense.
By taking Longevity Accelerator daily, you can purportedly support telomeres, which are components within your body linked directly to aging. With Longevity Activator, joint pain relief is a secondary benefit, while anti-aging is the primary benefit.
Key ingredients in Longevity Activator include Terminalia chebula fruit extract, purslane, turmeric, resveratrol, and Korean ginseng extract, among other unique ingredients. According to Zenith Labs, these ingredients can support cognitive and physical defenses against aging. Priced at $49 per bottle, Longevity Activator is backed by a 180 day moneyback guarantee.
Oweli Move Joint Health Formula
Oweli Move joint health formula is a dynamic joint health supplement for natural pain relief that is compiled from a potent group of extracts that add that much-needed lubricating complex to maintain healthy joints and mobility function. The ultra-smooth joint lubrication properties of the ingredients found in the Oweli Move joint supplement looks to help users optimize range of motion and comfort levels due to its unique ability to soothe inflammation and stiffness while providing vital cartilage and joint tissue protection.
With no additives or GMO extracts and free of harmful ingredients, the Move joint formula by Oweli is one of the newcomers on the list but is well respected due to their lab-tested, naturally-sourced product line that is earning the praise of its peers. For anyone who likes to cook, clean, walk or run, the Oweli joint health supplement quite literally helps aging individuals keep on moving with optimal flexibility, comfort and long-term protection of dynamic mobility.
With pure quality ingredients in this unique joint health supplement, users will be getting high profile extracts like glucosamine sulfate, boswellia, chondroitin sulfate, turmeric, quercetin, MSM and bromelain at a healthy dose with each pill consumed (3 capsules per serving size). Manufactured in FDA registered facilities and CGMP-compliant, what’s not to love about the newly released joint supplement for healthy mobility, Oweli Move.
Cymbiotika Ultimate Pain Balm
By applying a pain balm in conjunction with a joint pain supplement, you may be able to enjoy powerful benefits. Ultimate Pain Balm aims to be the leading joint pain relief balm. Priced at $56 per jar, Cymbiotika’s Ultimate Pain Balm is a fast-acting formula that provides healing, long-lasting relief, and comfort while stimulating blood flow and increasing circulation.
Key ingredients in Ultimate Pain Balm include organic MCT oil, beeswax, menthol, white camphor, peppermint oil, spearmint oil, and cinnamon oil. By mixing these ingredients in the right quantities and dosages, Ultimate Pain Balm may be able to provide rapid topical relief of joint pain, muscle pain, and stiffness.
Live Conscious Movewell+
The aptly-named Movewell+ is a nutritional supplement made with astaxanthin and hyaluronic acid. The supplement supports joint comfort and flexibility while encouraging healthy joints and cartilage.
The key ingredients in Movewell+ include astaxanthin, hyaluronic acid, and omega-3 fatty acids – all of which can be found in other supplements listed here. By combining all of these ingredients into a convenient formula, Movewell+ can purportedly provide powerful hydrating benefits for your joints. The antioxidants within the formula also claim to lessen oxidative problems and improve joint health by targeting inflammation within your joints – one of the key reasons we experience joint pain. At $35 per bottle, it’s also one of the best-value joint pain supplements on our list.
Prosper CBD Joint Restore Gummies
Prosper CBD’s Joint Restore Gummies contain a blend of ingredients to relieve joint pain in various ways – all in the tasty form of a gummy. Instead of swallowing a capsule or tablet daily, you can simply chew a gummy.
Each gummy contains 200mg of Boswellia serrata extract – an ingredient that can be found in many other supplements listed here. However, what distinguishes Joint Restore Gummies from competing joint pain products is the use of CBD. Each gummy contains a 20mg dose of CBD, an ingredient that many people use daily to support joint pain relief. It’s not the only CBD joint pain supplement on this list, but it’s one of the best-rated – although it’s also one of the most expensive.
CBDPure CBD Infused Cream
Many people apply CBD to their skin topically to relieve joint pain. With CBDPure’s CBD Infused Cream, you can enjoy targeted joint pain relief by applying the cream directly to your skin.
According to CBDPure, the CBD Infused Cream can soothe aches and pains and support a healthy range of motion by attacking pain at the source. You apply the cream directly to your skin to enjoy quick relief. Each tube contains 500mg of CBD along with smaller doses of willow bark and menthol to support the benefits further. Plus, all purchases are backed by a 90 day moneyback guarantee.
Advanced Bionutritionals Advanced Joint Support
Advanced Joint Support is a joint pain relief supplement from Advanced Bionutritionals. Priced at $70 per jar, Advanced Joint Support uses a 7-in-1 formula to attack joint pain in different ways.
Each four capsule serving of Advanced Joint Support contains 48mg of calcium, 1,500mg of glucosamine sulfate, 200mg of frankincense, and 480mg of white willow bark extract, among other unique ingredients. Although the key ingredient is glucosamine sulfate, Advanced Joint Support contains complementary ingredients to support these benefits further.
Nature Heals Proflexoral
Proflexoral is an 8-in-1 nutritional supplement that supports optimum joint health and mobility. Each three capsule serving contains active ingredients like Boswellia serrata resin extract, turmeric curcumin root, glucosamine, chondroitin, quercetin, MSM, L-methionine, and bromelain.
According to Nature Heals, the supplement was formulated by a medical doctor named Dr. Ralph La Guardia, who discovered the unique combination of ingredients on a recent trip to Japan. After giving the formula to his patients, Dr. La Guardia observed powerful and rapid joint relief. Each bottle of Proflexoral is made in the United States.
3 Naturals Triple Joint Health
3 Naturals makes a popular joint pain relief formula called Triple Joint Health. According to 3 Naturals, the supplement will soothe join pain, boost flexibility, relieve stiffness, tone done swelling, and even relieve cartilage using natural ingredients.
Triple Joint Health targets the two main causes of joint pain, including decaying cartilage and swollen joint tissue. To provide those benefits, Triple Joint Health uses a doctor-designed formula with herbs and plant extracts. Key ingredients include niacinamide, MSM, turmeric, Boswellia serrata, ginger, basil, and rosemary, among other ingredients.
Super Joint Support
Super Joint Support is a joint pain supplement created by the Healthy Back Institute’s Jesse Cannone. Designed to relieve joint pain throughout your body, Super Joint Support contains ingredients like glucosamine sulfate (1,000mg per serving), marine magnesium (1,000mg per serving), and type II collagen (500mg per serving), among other ingredients.
If you take four capsules of Super Joint Support per day, you could enjoy rapid support for joint pain via a convenient, all-in-one formula. The formula is packed with vitamins and minerals, and the formula can purportedly stimulate the regeneration of cartilage to restore youthful mobility. Described as “the holy trinity miracle for super fast and everlasting relief,” Super Joint Support is marketed online with dramatic claims and may be the right joint pain formula for you.
CellGrail Maximum Flex
Many people with joint pain have severe mobility issues. Maximum Flex, as the name suggests, claims to solve those issues. Made by CellGrail, Maximum Flex uses natural ingredients to support the areas between your bones, helping relieve joint pain.
By taking Maximum Flex daily, you can purportedly relieve bone and joint pain, reduce swelling of the joints, and help diminish morning stiffness while boosting mobility, among other ingredients. Active ingredients in Maximum Flex include glucosamine sulfate, chondroitin sulfate, frankincense, and turmeric.
NSP Nutrition Ultra Joint Relief Pro
NSP Nutrition’s Ultra Joint Relief Pro is a joint pain relief supplement that claims to reduce the risk of osteoarthritis and defeat other effects of aging, helping you stay strong while completing your workout program.
Marketed primarily to men, Ultra Joint Relief Pro claims to help you safely build and sculpt your physique, allowing you to complete your workout at the gym no matter how old you are. Priced at $30, Ultra Joint Relief Pro is one of the better-value options on our list. And, like other supplements listed here, it uses natural ingredients to support significant joint pain relief.
MindBody Matrix Pain Relief Cream
MindBody Matrix Pain Relief Cream is a topical remedy for joint pain. The cream was formulated with the goal of helping one million veterans eliminate joint pain, soothe arthritis, and permanently avoid pain.
With that goal in mind, the company claims to have spent $3 million researching and developing the cream, including $100,000 to build the LED light chamber used to manufacture the cream. After all of that research, the company settled on a formula with chamomile, lavender, lemon balm, aloe vera, tea tree, and other ingredients found in many topical treatments sold online today. MindBody Matrix Pain Relief Cream is priced at $60 and backed by a 60 day moneyback guarantee.
Flexotone is a joint pain relief supplement sold exclusively through Flexotone.com. Unlike other formulas listed here, Flexotone is not sold through pharmacies, retail stores, or online merchants. You can only buy it through the official website.
Flexotone makes many bold statements about its effectiveness. One customer cited on Flexotone.com claims that the formula completely eliminated her chronic arthritis pain even when morphine had no effect. Others claim to have experienced relief with Flexotone after decades of serious joint pain.
Although we’re skeptical of some of the statements made on Flexotone.com (like the fact that the supplement could be more powerful than morphine), Flexotone is backed by a 60 day moneyback guarantee.
Nutrition Hacks Joint Pain Hack
Joint Pain Hack from Nutrition Hacks is a popular joint pain relief supplement sold exclusively online. While other joint pain supplements simply claim to support healthy inflammation, Joint Pain Hack specifically claims to reduce inflammation. According to Nutrition Hacks, the supplement also soothes sore muscles, restores worn out joints, and improves flexibility and mobility, among other benefits.
If joint pain is keeping you from an active lifestyle, then Joint Pain Hack may be able to help. Joint Pain Hack even claims to offer faster relief than glucosamine and chondroitin, two of the most popular joint pain ingredients available today. According to Nutrition Hacks, Joint Pain Hack will rebuild cartilage, relieve pain, and rehydrate the joints to target joint pain.
Each tow tablet serving of Joint Pain Hack contains 1,000mg of glucosamine sulfate, 500mg of MSM, and 225mg of chondroitin sulfate, among other ingredients. By combining turmeric and bromelain with these active ingredients, Nutrition Hacks may have created a ‘hack’ for joint pain.
Best Joint Pain Supplements on Amazon
Some of the world’s best joint pain supplements can be found on Amazon, where they’re backed by thousands of positive reviews and average ratings over 4.5 stars out of 5.
Based on the same analysis that ranked the joint pain supplements above, here are the top-rated joint pain supplements on Amazon:
Move Free Joint Health
Move Free Joint Health is one of the best-known and best-rated joint health formulas available today. Made by Schiff, Move Free Joint Health is designed to support five signs of joint health, including mobility, comfort, strength, flexibility, and lubrication.
What really stands out about Move Free Joint Health is the top ratings: with 12,300+ reviews on Amazon, Move Free has an average rating of 4.5 stars out of 5, making it one of the best-rated joint supplements available here. Plus, with 120 capsules (40 servings) per box and a price point of just $18, Move Free offers better value than any other joint pain supplement on our list. It’s easily the best joint pain supplement on Amazon.
Vimerson Health Glucosamine Chondroitin Turmeric & MSM
Vimerson Health’s joint pain relief supplement tells you everything you need to know on the capsule: it contains glucosamine, chondroitin, turmeric, and MSM to relieve joint pain in multiple ways.
Like Move Free Joint Health, Vimerson Health’s joint pain supplement is backed by a stunning rating on Amazon: with 22,300+ reviews, the supplement has an average rating of 4.5 stars out of 5, with 87% of reviewers giving it 4 stars or better. That means most buyers seem to get effective joint pain relief via the supplement.
Vimerson Health’s Glucosamine Chondroitin Turmeric & MSM is another good-value pick. Priced at $17 for 90 capsules, the supplement offers some of the best value-per-dosage ratings on our list.
Instaflex is a joint pain support supplement that uses turmeric, resveratrol, Boswellia serrata extract, and type II collagen to support joint pain relief.
Priced at $57 per bottle, Instaflex is more expensive than other joint pain supplements sold on Amazon. It also has lower average ratings. With an average rating of 4.1 stars out of 5 from 3,900+ reviews, Instaflex may not relieve joint pain in everyone, yet thousands of people swear by it, taking Instaflex daily to relieve joint pain.
Jocko Joint Warfare
Jocko Joint Warfare is a joint pain relief supplement that uses anti-inflammatory ingredients to help alleviate joint pain, reduce joint inflammation, fight age and wear, and promote joint mobility and flexibility, among other effects.
Priced at $60 per bottle, Jocko’s Joint Warfare uses many of the same ingredients found in other supplements listed here, including curcumin, glucosamine, MSM, Boswellia serrata, and quercetin. By targeting inflammation within your joints, Jocko Joint Warfare may be able to promote long-term joint health, mobility, and flexibility.
How We Ranked the Top Joint Pain Relief Products
Every joint pain relief supplement claims to relieve joint pain. To separate the best joint supplements from the worst one, our editorial team considered all of the following:
Science-Backed Ingredients & Dosages: The most important thing to look for when comparing joint pain supplements is the use of science-backed ingredients and dosages. Some joint pain supplements have a carefully-curated selection of proven joint pain relief ingredients. Other joint pain supplements contain weak dosages of dozens of unproven ingredients – like unusual Asian herbal extracts or common vitamins you can get through any multivitamin supplement.
Uniqueness: Many people take MSM or glucosamine supplements for joint pain. Others take multivitamins. These supplements are common and cheap. We preferred supplements that contained unique and proven ingredients for joint pain (or were priced reasonably based on their common ingredients).
Doctor or Naturopath Formulated: Some of the world’s leading supplement companies employ naturopaths, medical doctors (MDs), PhDs, and other joint pain relief specialists. The more science and medicine were used to create a supplement, the higher we ranked it. Medical doctor approval was especially important.
Price & Value: Some people are willing to spend $100+ to relieve joint pain and improve mobility. Others want to spend less than $15 per month. We featured joint pain supplements for all different budgets, although we emphasized good value at every price.
Honest Advertised Benefits: Some joint pain supplement companies exaggerate their benefits. They claim to eliminate all joint pain within minutes, for example, or instantly cure serious injuries. Joint pain supplements can support joint pain relief, but they will not offer the same relief as anti-inflammatories, NSAIDs, or other over-the-counter drugs. In fact, FDA regulations prohibit supplements from being advertised as a cure, treatment, or preventative measure for a disease or illness.
Moneyback or Satisfaction Guarantee: Joint pain is complicated. Some people experience joint pain because of old athletic injuries. Others have conditions like osteoarthritis or rheumatism. Some people may experience rapid relief from a joint pain formula, while others find it’s completely ineffective. That’s why we preferred joint pain supplements with a moneyback or satisfaction guarantee. If it doesn’t work for you, you should be able to get a refund. The top manufacturers stand behind their products.
Manufacturer Reputation, Honesty, & Transparency: Joint pain supplement manufacturers come in all shapes and sizes. Some companies are honest, transparent, and reputable. Others are not. We preferred companies with a proven reputation for creating high-quality supplements.
Scientific Evidence for Joint Pain Supplements
Science tells us that certain vitamins, minerals, and nutrients can relieve joint pain. By taking the right joint pain supplement, you could improve mobility – even where drugs or therapies have failed.
Many people with joint pain take chondroitin daily to manage their condition. Along with glucosamine, chondroitin is one of the most popular joint pain supplement ingredients in the world. Chondroitin works because it’s a building block of cartilage. By taking a chondroitin supplement, you could support cartilage, which forms the cushion between your joints.
In this 2016 study, researchers found that chondroitin significantly improved knee pain in people with osteoarthritis. Participants took chondroitin or a placebo, with the chondroitin group reporting a 20% improvement in knee pain.
Glucosamine, meanwhile, is also backed by significant research. Like chondroitin, glucosamine supports the cartilage between your bones. It’s a building block for cartilage. In this study, researchers found that glucosamine sulfate can significantly improve symptoms of osteoarthritis, reducing pain and improving mobility in patients with the condition.
However, glucosamine doesn’t work for everyone, and some studies suggest glucosamine doesn’t work at all. In this 2013 study, researchers reviewed evidence on glucosamine and osteoarthritis. After analyzing dozens of double-blind trials, researchers found no significant difference between glucosamine and a placebo for improving symptoms of osteoarthritis.
Along with glucosamine and chondroitin, MSM is the third most popular joint pain supplement ingredient in the world. Many people have experienced joint pain for years – only to get relief through an MSM supplement. Methylsulfonylmethane (MSM) has been found to improve joint pain and mobility in people with osteoarthritis. Most MSM studies use a dose of 1,500mg to 6,000mg of MSM per day.
Turmeric is one of the most popular joint pain supplement ingredients available today. Many people with joint pain – or general inflammation issues – take turmeric daily to manage the condition. In this 2016 study, researchers reviewed evidence on turmeric and joint pain, concluding that taking 1,000mg of curcumin per day could significantly reduce arthritis pain and improve overall arthritis symptoms. Turmeric was found to reduce joint pain and improve arthritis symptoms across dozens of studies.
Although not as well-known as joint pain supplement ingredients above, Boswellia serrata is found in many supplements above. It may be one of the oldest joint pain remedies on this list: the ingredient has been used for centuries for joint pain. Today, joint pain relief supplements typically contain 100mg to 400mg of Boswellia serrata for joint pain. In one study, researchers found that Boswellia serrata was a possible anti-inflammatory agent, which explains why it could help with joint pain.
Bromelain is best known for being an enzyme in pineapples. However, studies show that bromelain may help with joint pain. Bromelain breaks down protein, which could reduce inflammation in people with certain types of arthritis. According to Arthritis.org, people with arthritis could support pain relief by taking a 500mg to 2,000mg bromelain supplement one to three times per day (ideally before meals).
Some joint pain supplements contain capsaicin. Capsaicin is also the active ingredient in many topical joint pain relief creams. Capsaicin is the active ingredient in chili peppers, and it’s prized for its medicinal properties. Studies show that capsaicin can relieve joint pain in many individuals, which is why many joint pain relief creams (like Capzasin-HP and Salonpas) use capsaicin as their active ingredient. Start with a mid-strength capsaicin cream (with 0.075% capsaicin) before working your way up to a stronger dose (like the 0.25% creams). For the maximum relief possible, consider a prescription-strength capsaicin patch, which uses 8% capsaicin to relieve pain.
Other common joint pain supplement ingredients include cat’s claw extract, which appears to have anti-inflammatory and immune-stimulating properties according to some small studies. The herbal extract reduced swelling 50% better than a placebo in one study.
Many joint pain supplements also contain stinging nettle extract. Like cat’s claw, stinging nettle extract appears to have anti-inflammatory properties. One study found that stinging nettle extract could suppress the cytokines linked to inflammatory joint disease.
Joint pain is a complicated issue. Your joint pain may not be the same as someone else’s joint pain. However, by trying a science-backed joint pain supplement, you could enjoy rapid relief from joint pain while boosting mobility and enjoying other benefits.
Joint Pain Supplement Side Effects
Side effects you may experience with joint pain supplements include headaches, dizziness, drowsiness, or digestive discomfort.
Side effects are rare when taking joint pain supplements. Most people who take joint pain supplements will not experience any side effects.
Generally, joint pain supplements are safe to take when used by healthy adults in normal dosages. If you start mixing your own formulas, exceeding the recommended dose, or taking high levels of certain ingredients, then you could be more likely to experience side effects.
If you have a medical condition or are currently taking medication, then talk to your doctor before taking a joint pain supplement to avoid any complications.
Joint Pain Supplement Dosages
Most joint pain supplements require you to take one to four capsules per day.
Joint pain supplements contain many different ingredients at different concentrations. Follow the dosage instructions on your joint pain supplement to avoid complications.
We know the recommended dosage of some popular joint pain ingredients. Studies show that a 750mg to 1,500mg dose of turmeric, for example, has been shown to support inflammation and help support joint pain relief in some people. Studies also show that glucosamine supplements work best in doses of around 1,500mg per day.
FAQs About Joint Pain Supplements
We get plenty of questions about joint pain, joint pain supplements, and similar issues. Here are answers to some of our most commonly asked questions.
Q: What is a joint pain supplement?
A: A joint pain supplement is a product that uses natural ingredients to relieve joint pain, improve mobility, and provide other benefits.
Q: Who should take a joint pain supplement?
A: Over 70% of older adults experience some level of joint pain. If you’re one of the millions of Americans with joint pain, then you may benefit from a joint pain supplement.
Q: What causes joint pain?
A: Joint pain is most often caused by a breakdown of cartilage in the area, which could occur because of age, injury, or disease. Joint pain can also be caused by swelling within the joint and surrounding areas, muscle tightness, muscle spasms, auto-immune disorders, diseases, and other issues. People experience joint pain for different reasons.
Q: What is arthritis?
A: Arthritis is a group of 100 diseases. These diseases affect your joints and the areas around your joints, like your muscles and tendons.
Q: What does arthritis mean?
A: The word ‘arthritis’ translates to ‘joint inflammation.’ Humans have dealt with arthritis and related conditions for millennia.
Q: What type of arthritis do I have?
A: Common types of arthritis include osteoarthritis, rheumatoid arthritis, fibromyalgia, gout, tendonitis, bursitis, and upper or lower back pain.
Q: How do I treat arthritis or joint pain?
A: Doctors typically recommend medication, exercise, hot and cold therapy, lifestyle and diet changes, surgery, or weight loss to treat arthritis or joint pain. Some doctors may also recommend drugs, supplements, or medicine in conjunction with these treatments.
Q: What do joint pain supplements do?
A: Most joint pain supplements use natural ingredients to support healthy inflammation throughout your body. When these ingredients travel to your joints, they may help lower inflammation in the area, reducing the sensation of joint pain.
Q: Can joint pain supplements provide long-lasting relief?
A: A good joint pain supplement could provide long-lasting relief from joint pain by targeting the root cause of the condition. Other joint pain supplements provide temporary, short-term relief.
Q: What’s the best joint pain supplement to buy?
A: Any of the top-ranked joint pain supplements on our list are among the best supplements available today.
Q: How much should I spend on a joint pain supplement?
A: A joint pain supplement should cost somewhere between $15 and $70, depending on the formula, the level of quality, and other factors.
Q: Does CBD relieve joint pain?
A: Some of the most popular joint pain relief supplements available today use cannabidiol (CBD) to relieve joint pain. Many people experience rapid relief from joint pain using CBD, although it does not work for everyone.
Q: Does turmeric relieve joint pain?
A: Turmeric may relieve joint pain by supporting inflammation. Turmeric is rich with an active ingredient called curcumin that appears to have anti-inflammatory effects. Many people take turmeric supplements daily to relieve joint pain.
Q: How do I take a joint pain supplement?
A: Most joint pain supplements are packaged into a capsule or tablet. You take one to two capsules or tablets daily (as recommended by the supplement company). Other joint pain supplements come in the form of creams, ointments, or powders.
Q: What causes arthritis?
A: There are many different types of arthritis, and they can be linked to different causes. Although arthritis has plagued humans for centuries, scientists know little about the causes of arthritis, and it’s unclear why arthritis affects some people but not others. We do know the cause of certain types of arthritis: gout, for example, is caused by uric acid buildup within the body.
Q: Am I too young to experience joint pain?
A: You’re never too young to experience joint pain. In fact, children can develop arthritis. Symptoms of childhood arthritis or joint pain can include swelling, fever, stiffness, rash, fatigue, and joint pain.
Q: Can I prevent arthritis?
A: You may be able to reduce your risk of certain types of arthritis by adjusting risk factors you can control. Although you can’t change your genetics, you could practice safe movement (like smart lifting strategies), avoid physical overload, lose weight, stop smoking, or get therapy for injuries, among other strategies.
Q: Can I exercise with joint pain?
A: Talk to your doctor about exercising with joint pain. Sometimes, exercise can make the issue worse. In other cases, exercise can be good for joint pain. Try performing exercises that reduce pressure on the joints (try water aerobics instead of sprinting, for example).
Q: What are the risk factors for joint pain?
A: You’re more likely to experience joint pain if you’re overweight, have previous injuries to your joints or muscles, repeatedly overuse your muscles, have arthritis, have depression, or have poor overall health. However, many people experience joint pain with none of these risk factors.
Q: What is osteoarthritis?
A: Osteoarthritis is a common type of arthritis that gets worse over time. Osteoarthritis occurs when your cartilage (the protective cushion between your bones) wears away, causing your joints to become painful and stiff.
Q: What is rheumatoid arthritis?
A: Rheumatoid arthritis is a chronic disease caused by swelling and pain in your joints. When left untreated, rheumatoid arthritis can deform your joints.
Q: What is bursitis?
A: Bursitis is a type of joint pain and arthritis caused by overuse, particularly overuse of the hips, knees, elbows, or shoulders.
Q: What is gout?
A: Gout is a type of arthritis caused by excess uric acid buildup. Too many crystals collect in your joints, leading to joint pain and swelling. It’s particularly common in the big toe.
Q: How should I treat joint pain?
A: Exercise, weight loss, anti-inflammatory drugs, topical treatments, joint pain supplements, and simple at-home treatments (like heating pads, ice, or soaking in a warm tub) can all be effective ways to treat joint pain.
Q: When should I see a doctor for joint pain?
A: You should see a doctor for your joint pain if you experience numbness, noisy joints (like a clicking, grinding, or snapping sound when moving the joint), painful or difficult movement, or loss of mobility due to your joint pain. You should also visit the doctor for joint pain if you have a red, hot, and swollen joint, which could be the sign of a serious issue. In general, you should see a doctor for joint pain if it’s interfering with daily activities.
Q: Will joint pain go away on its own?
A: Most joint pain is caused by the breakdown of cartilage between joints. It’s unlikely for joint pain to go away on its own, although arthritis may get worse and better over time.
Q: What are the best topical creams for joint pain?
A: Topical creams with capsaicin, CBD, methyl salicylate, and other ingredients could help relieve joint pain when applied directly to the skin.
Q: How do joint pain injections work?
A: If you aren’t getting joint pain relief through supplements or medications, then injections may be able to help. Joint pain injections include steroids, platelet-rich plasma therapy, and prolotherapy. Doctors inject special ingredients into your joints to stimulate recovery in the area. With some joint pain injection therapies, doctors may also remove fluid from the joints to speed up healing.
Q: What are the most common types of arthritis?
A: The most common types of arthritis are osteoarthritis (generally caused by wear and tear), rheumatoid arthritis (where the linings of multiple joints become inflamed), and psoriatic arthritis (an inflammatory type of arthritis that can cause raised or scaly patches on the skin).
Q: Is joint pain a symptom of COVID-19?
A: Approximately 15% of COVID-19 sufferers experience joint pain. It’s not a common symptom of COVID-19, but many experience the symptom. Nevertheless, the CDC does not list ‘joint pain’ as a symptom of COVID-19.
Q: How do I sleep with joint pain?
A: Many joint pain sufferers experience issues with sleep. If you’re having trouble sleeping with joint pain, then consider taking NSAIDs, supplements, or talking to a doctor about your joint pain.
Q: What is facet joint pain or facet syndrome?
A: Facet joint syndrome is a condition where you experience pain in the lower spine’s facet joints. Typically, the syndrome develops with age. Doctors may recommend surgery to get rid of facet joint pain.
Q: What is sacroiliac or SI joint pain?
A: Sacroiliac or SI joint pain is caused by injury to the joints in your spine and hips. This joint pain could spread to other parts of the body.
Q: Which foods cause joint pain?
A: According to the Arthritis Foundation, several foods have been linked to an increased risk of joint pain. Eating foods with too much sugar, trans fat, or saturated fat, for example, could increase the risk of joint pain. Eating too many omega-6 fatty acids or refined carbs could also make joint pain worse. Similarly, there appears to be a connection between MSG and alcohol consumption and joint pain.
Q: Can anxiety cause joint pain?
A: Many people are surprised to learn that there’s a connection between anxiety, depression, and joint pain. Studies show that stress and anxiety can increase the release of molecules that cause inflammation, increasing the risk of joint pain. Anxiety can also force you to overuse certain muscles and joints (say, by rapidly tapping your leg up and down), increasing the risk of joint pain.
Q: Can collagen supplements help with joint pain?
A: Many people take collagen supplements daily for anti-aging benefits or muscle growth. Collagen is the most abundant protein in the body, and it could help support cartilage between your joints to reduce joint pain. However, more research is needed to verify the connection between collagen and joint pain.
Q: Do changes in pressure cause muscle and joint pain?
A: Studies have shown that changes in air pressure can increase the risk of joint pain. As air pressure rises, it causes your muscles, tendons, and surrounding tissues to expand or contract, leading to joint pain.
Q: Can gluten cause joint pain?
A: People with celiac disease or a gluten sensitivity could experience joint pain after taking wheat or wheat products. Because your immune system responds improperly to gluten, it can increase the risk of excess inflammation in your joints, causing joint pain.
Q: Can dehydration cause joint pain?
A: Dehydration could increase the risk of joint pain. Your cartilage is made up mostly of water. When you’re dehydrated, it sucks water from the cushion between your joints, increasing cartilage breakdown and boosting the risk of joint pain.
Q: Can allergies cause joint pain?
A: An allergic reaction can increase inflammation, which could cause joint pain.
Q: Can cold weather cause joint pain?
A: Yes, cold weather can increase the risk of joint pain. Lower temperatures may be associated with changes in atmospheric pressure. When atmospheric pressure changes, it causes muscles and surrounding tissues to expand or contract, which could make joint pain worse.
Joint pain supplements all promise similar benefits: they all claim to support the relief of joint pain and boost mobility.
Some supplements genuinely work, providing rapid relief from joint pain in a way other remedies cannot.
- BioTRUST Joint 33X – learn more, buy here
- PureHealth Research Joint Support – learn more, buy here
- PhytAge Labs Joint Relief 911 – learn more, buy here
- Zenith Labs Joint N-11 – learn more, buy here
- ProJoint Plus – learn more, buy here
- 1MD MoveMD – learn more, buy here
- Nuzena Joint Support + – learn more, buy here
- Thrive Health Labs Joint Guard 360 – learn more, buy here
- Onnit Joint Oil – learn more, buy here
- UpWellness Golden Revive + – learn more, buy here
- Zenith Labs Longevity Activator – learn more, buy here
- Cymbiotika Ultimate Pain Balm – learn more, buy here
- Oweli Move Joint Health Formula – learn more, buy here
- Live Conscious Movewell+ – learn more, buy here
- Prosper CBD Joint Restore Gummies – learn more, buy here
- CBDPure CBD Infused Cream – learn more, buy here
- Advanced Bionutritionals Advanced Joint Support – learn more, buy here
- Nature Heals Proflexoral – learn more, buy here
- 3 Naturals Triple Joint Health – learn more, buy here
- Healthy Back Institute Super Joint Support – learn more, buy here
- CellGrail Maximum Flex – learn more, buy here
- NSP Nutrition Ultra Joint Relief Pro – learn more, buy here
- MindBody Matrix Pain Relief Cream – learn more, buy here
- Flexotone – learn more, buy here
- Nutrition Hacks Joint Pain Hack – learn more, buy here
- Move Free Joint Health – learn more, buy on Amazon
- Vimerson Health Glucosamine Chondroitin Turmeric & MSM – buy on Amazon
- Instaflex – learn more, buy on Amazon
- Jocko Joint Warfare – learn more, buy on Amazon
Choose any of the top-ranked joint pain supplements above to enjoy powerful, rapid, and sustained support for your joint pain problems.
The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.
Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.