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Blood Sugar Breakthrough Reviews (BiOptimizers) Is It Legit?

Blood Sugar Breakthrough is a nutritional supplement created by BiOptimizers. The supplement claims to optimize your blood sugar levels and enhance your metabolism.

By taking two capsules of Blood Sugar Breakthrough daily, you can purportedly improve exercise performance and muscle gain, stabilize your blood sugar levels and enjoy other benefits. The supplement is primarily marketed to diabetics, pre-diabetics, and others who struggle with blood sugar.

Does Blood Sugar Breakthrough live up to the hype? Or is it yet another diabetes supplement scam? Keep reading to discover everything you need to know about Blood Sugar Breakthrough and how the formula works.

What is Blood Sugar Breakthrough?

Blood Sugar Breakthrough is a diabetes supplement sold online through The supplement uses natural ingredients to stabilize blood sugar and promote healthy blood sugar levels.

By taking Blood Sugar Breakthrough daily, you can purportedly increase blood sugar uptake into muscles rather than fat cells, optimizing blood sugar while enhancing your metabolism.

The supplement also claims to neutralize oxidative damage (i.e. inflammation) from high blood glucose, improve carbohydrate metabolism, and promote a balanced inflammatory response, among other benefits.

Priced at $69 per bottle, Blood Sugar Breakthrough purportedly uses a range of science-backed blood sugar control ingredients at doses proven to be clinically effective. Because of these ingredients, Blood Sugar Breakthrough can purportedly have significant effects on blood sugar – even allowing diabetics to enjoy high-carb foods with “minimal health risks,” according to the official website.

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Blood Sugar Breakthrough Features & Benefits

According to, anyone who takes two capsules of Blood Sugar Breakthrough daily could experience the following benefits:

Increase Blood Sugar Uptake Into Muscles Rather than Fat Cells: When your body has excess levels of blood sugar and is unable to use that sugar for energy, it transfers it to your fat cells, allowing your body to use that energy at a later date. This effect was useful in ancient times for survival purposes. It’s less useful today when excess blood sugar can simply make you fat.

Improve Exercise Performance and Muscle Gain: Blood Sugar Breakthrough claims to improve exercise performance and muscle gain, helping you maximize performance from your workouts.

Improve Carbohydrate Metabolism: Carbohydrate metabolism is the rate at which your body burns carbs for energy. Carbs are an easy and accessible form of energy. When your body metabolizes carbs, it turns those carbs into usable energy instead of storing them as fat. Blood Sugar Breakthrough may purportedly improve your body’s carbohydrate metabolism.

Stabilize and Promote Healthy Blood Sugar Levels: Diabetics and pre-diabetics struggle to stabilize blood sugar levels. Some experience spikes in blood sugar levels after a meal, for example, while others experience wild fluctuations throughout the day. Blood Sugar Breakthrough claims to stabilize and promote healthy blood sugar levels.

Neutralize Oxidative Damage from High Blood Glucose: High blood glucose can cause inflammation, also known as oxidative damage. As levels of free radicals rise in your body, it increases oxidation and causes inflammation. Blood Sugar Breakthrough claims to neutralize the oxidative damage caused by high blood glucose.

Improve Energy and Overall Well Being: Blood Sugar Breakthrough claims to improve your energy and overall well being. Many diabetics struggle with energy. With blood sugar levels fluctuating throughout the day, it can be difficult to maintain stable energy, leading to tiredness, mental fog, and other issues. By taking two capsules of Blood Sugar Breakthrough daily, you can purportedly improve energy levels and overall wellbeing.

Promote Healthy Insulin Sensitivity: Diabetics and pre-diabetics struggle with insulin sensitivity. Your body no longer produces enough insulin to regulate glucose in your blood (your blood sugar). Blood Sugar Breakthrough claims to promote healthy insulin sensitivity using natural ingredients.

Support Weight Loss: When used in combination with diet and exercise, Blood Sugar Breakthroughs may help you lose weight. The supplement claims to boost energy, making it easier to lose weight. But the formula can also purportedly increase mitochondrial uncoupling, forcing your body to burn more calories as heat (similar to thermogenic diet pills sold online today).

Normalize Mood Swings, Brain Fog, Hormones, Stress Response, and Cravings: Many diabetics and pre-diabetics experience mood swings, cravings, brain fog, energy swings, and other physical and cognitive issues because of their condition. According to BiOptimizers, Blood Sugar Breakthrough will normalize mood swings, energy swings, brain fog, and cravings due to blood sugar fluctuations – while also balancing hormones and stress response.

Inhibit Carb Digestion and Absorption: By taking Blood Sugar Breakthrough daily, diabetics may purportedly avoid the negative effects of a carb-rich meal, according to The formula claims to inhibit carb digestion and absorption in the gut, making it harder for your body to absorb (and store as fat) the carbs you eat.

Promotes a Balanced Inflammatory Response: Inflammation is the root cause of many diseases and illnesses. Many diabetics have high levels of inflammation because of their condition. Blood Sugar Breakthrough claims to promote a balanced inflammatory response, helping support normal inflammation throughout your body.

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Blood Sugar Breakthrough Ingredients

Many diabetes supplements claim to help diabetics support blood sugar and enjoy other powerful benefits. However, not all of these supplements work as advertised. Good ingredient profiles separate the best and worst diabetes supplements from one another.

To help balance blood sugar, Blood Sugar Breakthrough contains minerals like biotin and chromium in very large dosages (6,667% and 1,143% of your Daily Value, respectively).

The formula also contains a proprietary blend containing unique ingredients like bee propolis, benfotiamine, alpha-lipoic acid, and fucoxanthin.

Other plants and herbal extracts in Blood Sugar Breakthrough include bitter melon extract, cinnamon bark extract, and Panax ginseng, all of which are popular in other diabetes supplements sold online today.

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Here are some of the biggest ingredients in Blood Sugar Breakthrough and how they work:

Biotin: Biotin supplements have been shown to improve glucose and triglyceride levels in people with type 2 diabetes while also reducing pain from diabetes nerve damage, according to Peace Health. Many diabetics take biotin supplements daily for this reason. There’s 6,667% of your recommended daily value (DV) of biotin in each serving of Blood Sugar Breakthrough.

Chromium: Chromium is an essential mineral. Studies show that diabetics and pre-diabetics tend to have lower levels of chromium than others. That’s why many doctors recommend taking a chromium supplement to help manage the condition. Chromium has been shown to promote healthy blood sugar levels, and Blood Sugar Breakthrough contains a significant dose of chromium (1,143% DV).

Bee Propolis: Bee propolis is one of the more unique ingredients in Blood Sugar Breakthrough. While other ingredients are found in other diabetes supplements, bee propolis is less common. Some studies have shown that bee propolis supplements can have direct and indirect hypoglycemic effects, potentially helping diabetes control and support healthy blood sugar. In [1] this study, for example, researchers gave bee propolis to mice with diabetes and observed hypoglycemia (blood sugar lowering) effects.

People Also Read: Glucofort Review

CyanthOx: CyanthOx is a proprietary formula with 30% proanthocyanidins by concentration. Anthocyanin is a phytochemical linked to inflammation. It’s found in blueberries, blackberries, and other dark fruits, giving the fruits their distinctive color. Studies show that these anthocyanins and other ingredients could support various benefits, including inflammation and blood sugar control.

Alpha Lipoic Acid: Alpha-lipoic acid (ALA) is best-known as a diabetes supplement. Studies show that ALA could support blood sugar in multiple ways. Alpha-lipoic acid is a vitamin-like chemical that works as an antioxidant. You can get ALA through foods like spinach, potatoes, and broccoli. Alternatively, many diabetics take ALA daily as a supplement, helping their bodies support blood sugar by targeting inflammation.

Other Plant & Fruit Extracts: Blood Sugar Breakthrough contains several other plant and fruit extracts linked to blood sugar in multiple studies, including many popular ingredients found in other diabetes supplements sold online today. Blood Sugar Breakthrough contains bitter melon fruit extract, GlucoVance, cinnamon bark extract, and Panax ginseng, among other ingredients.

How Blood Sugar Breakthrough Targets Blood Sugar

According to, Blood Sugar Breakthrough targets blood sugar by acting on seven mechanisms within the body. By activating AMPK, stimulating Glut4 receptors, and mimicking insulin, the ingredients in Blood Sugar Breakthrough may purportedly help diabetics support blood sugar in various ways.

Here are the seven ways in which Blood Sugar Breakthrough targets blood sugar, according to BiOptimizers:

1) Stimulates Glut4 Receptors: First, Blood Sugar Breakthroughs may purportedly stimulate your Glut4 receptors, which are the receptors found in fat, heart muscles, and muscle cells. When your insulin receptors are stimulated, it brings Glut4 to the cell surface, allowing glucose to move into the cells. Blood Sugar Breakthrough uses ingredients like cinnamon, alpha-lipoic acid, and banaba leaf extract to help bring Glut4 to the cell surface.

2) Activates AMPK: Like many supplements sold online today, Blood Sugar Breakthrough claims to activate AMPK, a source of energy in your cells. By activating AMPK, the formula tells your cells to bring in more glucose, increasing cellular energy and leading to a noticeable improvement in physical and cognitive energy.

3) Slows Carb Digestion and Absorption: As mentioned above, Blood Sugar Breakthrough claims to slow down the absorption and digestion of carbs. To do that, Blood Sugar Breakthrough uses ingredients like banaba leaf extract, Innoslim, and bitter melon extracts, all of which have been shown to slow the digestion of carbs and the absorption of glucose. Because of these ingredients, Blood Sugar Breakthrough may purportedly significantly reduce the glycemic index of your meals,” making it less likely for blood sugar levels to spike and crash.

4) Increases GLP-1: Blood Sugar Breakthrough may purportedly increase glucagon-like peptide 1 (GLP-1), which has anti-inflammatory effects and counteracts the insulin resistance caused by inflammation. Cinnamon increases GLP-1, for example.

5) Mimics Insulin: Some of the ingredients in Blood Sugar Breakthrough purportedly work as insulin mimetics, mimicking the effects of insulin in various ways. To do that, Blood Sugar Breakthrough uses ingredients like seabuckthorn, bitter melon, and banaba leaf extracts. These ingredients have components that stimulate insulin signaling pathways, helping cells take up glucose from the bloodstream more rapidly.

6) Activates PPAR-Alpha and PPAR-Gamma: PPAR-alpha and PPAR-gamma are proteins that turn on genes that control metabolism. PPAR-alpha increases fat breakdown in the liver. Your body activates PPAR-alpha during caloric restriction or ketosis, signaling your body to burn fat for energy. Your body activates PPAR-gamma to increase insulin sensitivity and insulin secretion. To achieve these benefits, Blood Sugar Breakthrough uses ingredients like cinnamon, alpha-lipoic acid, bitter melon, and quercetin, all of which either increase or activate these proteins.

7) Improve Mitochondrial Function and Uncoupling: Your mitochondria provide energy for each cell. Bitter melon extract and fucoxanthin may purportedly increase mitochondria fat breakdown and uncoupling, leading to heat loss. According to some animal studies, bitter melon extract can also lead to fat loss.

Because of these effects, BiOptimizers claims Blood Sugar Breakthrough can help stabilize normal blood sugar levels while using proven and reputable ingredients.

Blood Sugar Breakthrough Ingredients Label

Blood Sugar Breakthrough contains over a dozen ingredients linked to blood sugar, energy, metabolism, and more. Here are all of the ingredients in Blood Sugar Breakthrough, according to the ingredients label:

  • 2,000mcg of biotin (6,667% DV)
  • 400mcg of chromium (1,143% DV)
  • 608mg of a proprietary blend with bee propolis, CyanthOx 30 Hippophae rhamnoides L fruit extract (with 30% proanthocyanidins), benfotiamine, R-alpha lipoic acid, banaba leaf extract (with 20% corosolic acid), Gymnema Sylvestre leaf extract, and fucoxanthin (10%)
  • 200mg of Glycostat bitter melon fruit extract
  • 100mg of GlucoVantage dihydroberberine
  • 100mg of Cinnulin PF cinnamon bark extract (20:1)
  • 75mg of Innoslim

Other ingredients, including hypromellose (to create the capsule), microcrystalline cellulose, silicon dioxide, and magnesium stearate

Blood Sugar Breakthrough Pricing

Blood Sugar Breakthrough $69 per bottle, although the price drops by 10% if you subscribe and save.

Here’s how pricing breaks down when ordering through

One Time Purchase: $69 per bottle

Subscribe & Save (10%): $62.10per bottle

BiOptimizers offers free shipping on orders over $90. You also get a free copy of “The Biological Optimization Blueprint” on orders over $150 and an additional free bonus gift for orders over $400.

Blood Sugar Breakthrough Refund Policy

Blood Sugar Breakthrough is backed by a 365-day moneyback guarantee. You can request a complete refund on your purchase within 365 days if you’re unsatisfied.

If Blood Sugar Breakthrough did not impact your blood sugar, or if you’re unhappy with the effects of Blood Sugar Breakthrough for any reason, then you are entitled to a complete refund.

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About BiOptimizers

BiOptimizers is a nutritional supplement company launched in 2004. The company was founded by Wade Lightheart (President) and Matt Gallant (CEO). Wade watched his 23-year old sister pass away from cancer and was motivated to launch a company to support health and wellness in others. Matt later helped his best friend lose 191lbs in 18 months and transform his life – and he knew he was on the right path.

Before launching BiOptimizers, Wade and Matt were both trainers working with pro athletes and other high performers. They met in the gym, struck up a friendship, and started a business.

BiOptimizers make Blood Sugar Breakthrough in an FDA-approved, GMP-certified facility in the United States.

You can contact BiOptimizers via the following:

Email Form:

Phone: 1-800-719-2467

Mailing Address: 5470 Kietzke Lane, Suite 300, Reno, NV 89511

Final Word

Blood Sugar Breakthrough is a diabetes supplement that uses natural ingredients to support blood sugar in various ways.

By taking two capsules of Blood Sugar Breakthrough daily, you can purportedly promote healthy blood sugar levels, support weight loss, boost energy, and enjoy other benefits.

To find out more about Blood Sugar Breakthrough or to buy the supplement today, visit online at



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Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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