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Immune 11X Reviews (UpWellness) Do the Ingredients Work?

Compared to the past, the likelihood of experiencing colds and cases of flu because of seasonal changes has heightened more than ever. What does this suggest about our immune systems and the prevalence of pathogens and toxic players? How can one attain a protective shield against unwanted, chronic illnesses? This is where it is best to introduce Immune 11X. In the opinion of the creators, UpWellness LLC, Immune 11X not only considers the immune function as one but as two parts. Such an approach is believed to give rise to wellness all around. Have we gotten your full attention? If yes, the purpose of this review is to shed light on the effects that Immune 11X may have on one’s health.

What is Immune 11X?

As the name of the supplement alludes to, Immune 11X is a dietary supplement that supports the immune system and the liver and lung functions. Dubbed an 11-in-1 solution, the team at UpWellness is firm on suggesting that this supplement may provide a natural defense against environmental pathogens that cross our paths daily. How have they achieved this? Before exploring UpWellness’ proposition, let’s acquaint ourselves with the thought process that went into Immune 11X.

How does Immune 11X work?

Dr. Joshua Levitt explained that Immune 11X had been founded to address our innate immune system. He defined it as “the part of your immune system that is “built-in,” emphasizing that “it’s [the] the first line of defense against invasion.” Although our immune system also encompasses a part called the adaptive immune system, given that its role is to learn from horrid experiences, he decided to focus on the former. This makes sense, given that one’s health is either glorified or deteriorated by the innate immune system.

Having said that, individuals may wonder, “well, what indicates a healthy innate immune system?” If it can reinforce physical barriers, recruit white blood cells, activate proteins to attack pathogens, destroy and dispose of toxins and stimulate the adaptive immune system to learn from an attack, then it is healthy. Otherwise, individuals are likely to experience fatigue, respiratory problems, musculoskeletal pain, fluctuations of digestion, and further chronic illnesses.

After gathering and evaluating immunological studies, combined with his own experience as a naturopath, Dr. Joshua Levitt believes he has formulated a solution that contains therapeutic levels of each ingredient for a healthy immune system.

What does the Immune 11X formula consist of?

The ingredients that made it to Immune 11X are in the form of vitamins and adaptogenic herbs. To understand the extent to which Dr. Levitt’s thought process has been reflected in Immune 11X, we must analyze the following ingredients (quantities reflect one serving of 2 capsules):

Vitamin A (750mcg)

Vitamin A is a type of micronutrient required for the maintenance of vision and growth. Its critical role in developing and regulating the immune system has garnered it the title of the “anti-inflammation vitamin.” Matter-of-factly, a group of researchers has since concluded that it plays “both promoting and regulatory roles in both the innate immune system and adaptive immunity,” allowing them to conclude that Vitamin A can enhance defense against infectious diseases [1]. However, one study discovered that taking Vitamin A in excess can limit innate immune response while preventing the adaptive immune system from learning [2]. So, people must stick to the recommended 700mg to 900mg daily.

Vitamin C (230mg)

Dubbed an essential micronutrient, Vitamin C is a well-known and potent antioxidant that contributes to immune defense by maintaining cellular functions at both the innate and adaptive immune system layers. As summarized by a duo of researchers, it “supports epithelial barrier function against pathogens and promotes the oxidant scavenging activity in the skin, thereby potentially protecting against oxidative stress.” They also went as far as suggesting a dietary intake of 100mg to 200mg/day, a range suitable for optimizing tissues and cellular levels [3].

Vitamin D3 (25mcg)

One review analyzed the effects of vitamin D (yet another micronutrient) on the immune system. Although this relationship has been realized for over 30 years, the team believes that there’s a new way through which vitamin D might play a significant role. Primarily, the researchers argued that vitamin D’s metabolizing enzymes are crucial for normal immune responses, and for this to hold, a substrate 25OHD must be available. Otherwise, both the innate and adaptive immune systems will face negative consequences [4].

Zinc (12mg)

Zinc is a type of mineral that researchers view as an indispensable component of the immune system. Most importantly, it is trusted to help mediate T-cell events. Found within the immune system, T-cells have been tasked with focusing on foreign particles/specific antigens. Nevertheless, a group of researchers who reviewed its effect on the immune system stressed the importance of maintaining healthy levels. Why? Because zinc deficiency has supposedly been correlated with high hospitalization [5]. Another source highlighted that a deficiency could suppress both innate and adaptive immune systems, as zinc on its own acts as a second messenger in a variety of cellular activities [6].

N-Acetyl-Cysteine (300mg)

N-acetyl-cysteine (NAC) is an antioxidant derived from the amino acid L-cysteine. At present, it has been deemed vital support for both the immune system and lung function. Speaking of immune function, one study looked at the effect of adding NAC to conventional treatments for oxidative stress, inflammatory factors, and radiological changes in patients with community-acquired pneumonia. In the end, the researchers found that based on positive changes to plasma levels of malondialdehyde- and tumor necrosis factor-a, the “treatment with NAC may help to reduce oxidative and inflammatory damage [7].” As for its effect on the liver, one study proved that NAC could serve as a potential treatment for hepatotoxicity [8].

ALSO READ: Best Mushroom Supplements – Top Medicinal Mushroom Products

Cordyceps Fruiting Body (250mg)

Cordyceps is a variety of mushrooms that have been celebrated for their immune-enhancing properties. One source that appraised cordyceps as an herbal drug went over several studies before concluding that it affects both innate and adaptive immune systems. Moreover, it is believed to have a modulating effect on the gut system, which may heighten influence over immune-related activities [9]. Additionally, another recent review that took a similar route reported that “total extracts using water or 50% ethanol and polysaccharides from [cordyceps] could be used to treat tumors, allergies, and viral infections [10].”

Skullcap Root Extract (240mg)

Skullcap root is an herb popular among Asian cultures and medicinal practices. In particular, it has been liked for its anti-inflammatory, anti-allergic, and anti-viral activities. That said, one team that previously found skullcap’s effectiveness in preventing allergen permeation and regulating immune balance decided to fractionate skullcap into five fractions (i.e., hexane, chloroform, ethyl acetate, butanol, and water). In so doing, they found that hexane was the one to significantly suppress the production of Th2 mediated cytokines while increasing Th1-mediated cytokines. In other words, they noted that this fraction was the most linked to immune balance [11].

Astragalus Membranaceus Root (200mg)

Astragalus is a staple in traditional Chinese medicine (TCM) because of its rich antioxidants and antiviral properties. Aside from its immune-enhancing properties, this herb could help the body better respond to stress, lower blood sugar, may help reverse fatigue and loss of appetite, and reduce symptoms in people with allergic rhinitis or hay fever [12]. One source that summarized the effects of astragalus on health referenced scientific evidence when they stated that it could “help people recover faster and living longer,” adding that “it may help prevent colds.”

Andrographis Paniculata Leaf Extract (100mg)

Andrographis Paniculata leaf extract has supposedly been used to treat infectious diseases, loss of appetite, and fever-causing diseases [13]. In fact, a 60-day feeding trial that looked at its effect on growth, immunomodulation, and disease outbreak, primarily on Aeromonas hydrophila, found that the extract at a level of 2% could improve growth, immunity, and disease resistance against the culprit by enhancing the innate immune system [14].

Green Tea Leaf (100mg)

Green tea is a beverage that has convinced society when it comes to improving different areas of health. Its primary component, epigallocatechin-3 gallate, is the one deemed responsible for an array of benefits. Speaking of health, a literature review on green tea consumption recapitulated that it could treat metabolic disorders such as obesity, type II diabetes, and cardiovascular risk factors. However, the researchers also noted that more human studies are needed to confirm these benefits, as most are animal models [15]. That said, a study that addressed its immunomodulatory capacities confirmed that green tea does, in fact, serve such a role [16].

Quercetin Dihydrate (100mg)

Quercetin dihydrate is a plant pigment that has been favored for its antioxidant and anti-inflammatory properties. One study that looked at the effects of quercetin concluded that it might increase the secretion of immune molecules (i.e., immunoglobulin and tumor necrosis factor-a), which might explain why it has the ability to improve immune function [17]. Another source argued quercetin’s favor, as the pigment is trusted to ameliorate liver inflammation and fibrosis [18].


Frequently Asked Questions (FAQS)

Is Immune 11X safe?

Based on the ingredient list and the dosing, individuals can conclude that Immune 11X is safe for ingestion. All the listed ingredients come from natural sources and have been generally accepted by the scientific community as safe dietary components.

How should Immune 11X be implemented?

To give the immune system what it requires for optimal support, individuals are asked to take two Immune 11X capsules daily with an adequate water source.

Will Immune 11X interact with medications?

Unfortunately, there is never a straightforward answer to this question. It really boils down to the medication and one’s health. Therefore, this is a question that requires the attentiveness of a health practitioner. Having said that, Dr. Levitt claims that there may be interactions with blood-thinning medications. In this case, it should either be halted or taken as recommended by a health practitioner.

Is Immune 11X necessary for people who follow a healthy lifestyle?

Even with proper eating habits and physical movement, individuals can easily be at risk of an attack by pathogens. Many of the toxins in our very Earth are unseen to the naked eye, and as a result, it becomes imperative to have the extra protection provided by Immune 11X.

How long will it take to receive Immune 11X orders?

Orders shipped within the U.S. can take anywhere between three and five business days and longer elsewhere in the world.

Is Immune 11X protected by a money-back guarantee?

Yes, Immune 11X has been protected by a 60-day money-back guarantee. If this supplement neither provided comfort nor support, individuals can contact customer service to initiate the refund processes. This can be achieved in one of the following ways:

  • Email: or
  • Phone: +1 (800) 876 2196
  • Mailing Address: 4301 31st St N Building B, St Petersburg, FL 33477

How much does Immune 11X cost?

Each Immune 11X bottle contains 60 capsules enough to last one month. Here is a price’s breakdown worth assessing:

  • 1 Immune 11X bottle: $37 each
  • 3 Immune 11X bottles: $35.25 each
  • 6 Immune 11X bottles: $23.50 each


Meet the Creators

Starting with the creator of this formula, Dr. Joshua Levitt is a naturopathic doctor and founder of supplements company UpWellness LLC. He also happens to work at Whole Health, i.e., a natural family medicine clinic in Connecticut, U.S. As maintained on the UpWellness official website, the company was founded on his philosophy of “nutrients-living,” which he defines in the most “broadest possible way.” What does that mean? Well, to him, nutrients aren’t just the nutritious aspect of food, but at large, one’s way of life and the impact that good and poor decisions can have on one’s health entirely.

Final Thoughts

To recap, when strengthening the immune system, two factors need to be considered, one, the innate immune system, and two, the adaptive immune system. The former is the first line of defense, while the latter notes how best to defeat pathogens should they arise again. Immune 11X has been formulated to target the innate immune system; however, the listed ingredients have scientific evidence suggesting that both areas can be enhanced. In addition, this formula may tend to different organs including, but not limited to the lungs, liver, and gut functions. Having a solution that serves multiple purposes is reassuring, especially when most supplements focus on one primary issue. Moreover, having an accredited expert determine what should and shouldn’t go inside Immune 11X makes the formula and listed prices valuable. To learn more about Immune 11X, visit here>>>.

RELATED: Best Immunity Boosters: Review Top Immune System Supplements

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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