Aspirin rated as good as stroke-prevention drug

Associated Press

BOSTON — Aspirin works just as well as Coumadin, the granddaddy of stroke drugs, in helping most patients avoid recurrent strokes, according to a study aimed at settling a longstanding question among doctors.

Many doctors suspected that Coumadin, known generically as warfarin, was more effective but that aspirin was safer. This study challenges both views, showing the two drugs are equal in both respects, said Dr. J.P. Mohr, a neurologist at Columbia-Presbyterian Medical Center in New York who led the research.

Both aspirin and Coumadin work by thinning the blood, warding off clots that can block blood vessels.

The study, published in today’s New England Journal of Medicine, looked at patients who had already suffered the most common kinds of strokes — those that happen when a clot that forms outside the heart obstructs the flow of oxygen-carrying blood to the brain.

However, Coumadin remains superior for some patients. Earlier research has shown that the drug is more effective than aspirin in preventing additional strokes in patients whose first stroke stemmed from clots that formed inside the heart.

In the latest study, researchers tested the two drugs on 2,206 patients for two years at 48 hospitals around the country.

Almost 18 percent in the Coumadin group died or suffered another stroke, compared with 16 percent of those on aspirin. The difference was not considered statistically significant. Also, both drugs caused low rates of bleeding as a side effect.

The findings may actually give an edge to aspirin, because it is cheaper and demands less medical supervision, said Dr. William Powers, a brain researcher at Washington University in St. Louis who wrote an accompanying editorial.

Aspirin might cost about $10 for a year’s worth of treatment. Coumadin and the necessary blood tests can together cost several hundred dollars.

Coumadin has been used for about 50 years to combat stroke. Aspirin’s benefit for stroke patients was widely recognized about 30 years ago.

About 160,000 Americans die each year from strokes. Strokes are the nation’s leading cause of serious, long-term disability.

The study was sponsored by the National Institutes of Health.

Copyright ©2001 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

Talk to us

> Give us your news tips.

> Send us a letter to the editor.

> More Herald contact information.

More in Local News

Marysville
1 pedestrian dead after car crash on I-5 south of Marysville

Around 5 p.m., a car crashed into a pedestrian on I-5. Investigators were working to determine exactly what happened.

A man walks by Pfizer headquarters, Friday, Feb. 5, 2021, in New York. Pfizer will spend about $43 billion to buy Seagen and broaden its reach into cancer treatments, the pharmaceutical giant said. (AP Photo / Mark Lennihan, File)
Pfizer backs out of Everett manufacturing plant after $43B Seagen deal

Pfizer finalized the acquisition of the Bothell-based cancer drug developer in December.

A view of one of the potential locations of the new Aquasox stadium on Monday, Feb. 26, 2024 in Everett, Washington. The site sits between Hewitt Avenue, Broadway, Pacific Avenue and the railroad. (Olivia Vanni / The Herald)
20 businesses could be demolished for downtown Everett stadium

Some business owners say the city didn’t tell them of plans for a new AquaSox stadium that could displace their businesses.

Kathy Purviance-Snow poses for a photo in her computer lab at Snohomish High School on Tuesday, Feb. 27, 2024, in Snohomish, WA. (Annie Barker / The Herald)
To ban or embrace ChatGPT? Local teachers fight AI with AI — or don’t

“It has fundamentally changed my teaching in really stressful and exciting ways,” an EvCC teacher said. At all levels of education, ChatGPT poses a tricky question.

In this Feb. 5, 2018, file photo a Boeing 737 MAX 7 is displayed during a debut for employees and media of the new jet in Renton, Wash. (AP Photo/Elaine Thompson, File)
FAA gives Boeing 90 days to develop plan to fix quality, safety issues

The agency’s ultimatum comes a day after a meeting with CEO Dave Calhoun and other top Boeing officials in Washington, D.C.

Madi Humphries, 9, Rose Austin, 13, and Eirene Ritting, 8, on Thursday, Jan. 25, 2024 in Bothell, Washington. (Olivia Vanni / The Herald)
No grades, no teachers: Inside a Bothell school run by student vote

Each day at The Clearwater School, 60 students choose their own lessons. It’s one vote per person, whether you’re staff or student.

SonShine Preschool inside First Baptist Church Monroe is pictured Friday, March 1, 2024, in Monroe, Washington. (Ryan Berry / The Herald)
SonShine preschool in Monroe to close at the end of the year

The preschool, operated by First Baptist Church, served kids for 25 years. School leadership did not explain the reason behind the closure.

Two troopers place a photo of slain Washington State Patrol trooper Chris Gadd outside WSP District 7 Headquarters about twelve hours after Gadd was struck and killed in a collision on southbound I-5 about a mile from the headquarters on Saturday, March 2, 2024, in Marysville, Washington. (Ryan Berry / The Herald)
State trooper killed, 1 arrested in crash on I-5 near Marysville

Authorities said Trooper Chris Gadd had been stopped along the freeway around 3 a.m. near 136th Street NE. A Lynnwood driver, 32, was arrested.

Providence Hospital in Everett at sunset Monday night on December 11, 2017. Officials Providence St. Joseph Health Ascension Health reportedly are discussing a merger that would create a chain of hospitals, including Providence Regional Medical Center Everett, plus clinics and medical care centers in 26 states spanning both coasts. (Kevin Clark / The Daily Herald)
Following lawsuit, Providence commits to improved care for Deaf patients

Three patients from Snohomish County sued Providence in 2022 for alleged Americans with Disabilities Act violations.

Cars drive through snow along I-5 in Snohomish County, Washington on Thursday, Jan. 11, 2024.  (Annie Barker / The Herald)
In March, 7 p.m. sunsets are back for Western Washington

Washingtonians will finally start seeing more sun starting March 10. But a little more winter could be on the way first.

One of the parking lots at Stevens Pass Thursday afternoon on December 30, 2021.  (Kevin Clark / The Herald)
Stevens Pass to charge $20 for parking reservations on busy days

Two-thirds of spaces will remain free for early arrivers on weekends. Cars with four or more occupants can also park free.

Lynnwood
Days after shootout with Lynnwood police, suspect checks into hospital

Police learned the 18-year-old was in a hospital in Portland, Oregon. His alleged role in the shooting remained unclear.

Support local journalism

If you value local news, make a gift now to support the trusted journalism you get in The Daily Herald. Donations processed in this system are not tax deductible.