Have you been taking probiotic supplements only to be deceived by the claims made? Can’t seem to find a good supplement without worrying about losing money or wasted efforts? If the answer is yes, these are common issues most people face, hoping to find solace in the dietary supplement space. While it is true that some supplements might not be a good fit, there is also the fact that some products were not created with the best of intentions. Companies that aren’t transparent with their processes, supplement facts, and claims exist, and people need to find ways to avoid them. Fortunately, our editorial team took on this challenge recently and found a probiotic supplement that will likely make people happy with this new option. They are all about delivering products that are safe, useful, and backed by science, and they have proven their commitment in several ways. This is where it is fitting to introduce the GLP-1 Probiotic.
What is the GLP-1 Probiotic?
The GLP-1 Probiotic is a dietary supplement designed to naturally curb cravings, promote weight loss, and build a robust, healthy, diversified gut microbiome. What sets this probiotic supplement apart from its competitors is that it contains live probiotics from the human gut. In fact, the creators, Pendulum, insist that this approach naturally enhances GLP-1 production, which in turn regulates the different aspects of metabolism. Our editorial team was undoubtedly taken aback by the fact that probiotics can stimulate GLP-1 production, especially seeing the hype around Ozempic and similar medications. The latter case, however, has several scary side effects, with little to none on Team GLP-1 Probiotic. This raises the question of effectiveness, and to answer this, we need to understand the role that the GLP-1 hormone plays in our body.
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How does the GLP-1 Probiotic work?
The GLP-1 Probiotic supplement, as the name suggests, aims to increase GLP-1 levels by increasing the presence of science-backed probiotic strains in the body. Glucagon-like peptide-1 (GLP-1) is a hormone that stimulates insulin release, reduces glucagon in the body (known to raise blood sugar levels), and slows digestion to promote increased satiety. The Pendulum team maintains that as we consume food, a number of metabolic processes are triggered in the body.
Our probiotics (or good bacteria) help break down fibers into short-chain fatty acids (SCFAs) such as butyrate, acetate, and propionate in the gut microbiome. This trio secretes essential proteins (P9 is one of them) and stimulates mucin rejuvenation. Butyrate and P9 are among the fundamental factors that stimulate GLP-1, which, as noted earlier, dictates several aspects of our metabolic function. In fact, the rate at which GLP-1 production is stimulated determines one’s overall appetite, contributing either to weight loss or weight gain.
One study that looked at the beneficial metabolic effects of a probiotic on GLP-1 hormone secretion concluded that butyrate did increase GLP-1 secretion from intestinal L-cells, adding that protective metabolic effects are possible, ultimately reducing the risk of obesity and diabetes. To summarize, specific probiotic strains release key SCFAs that not only go on to alter the gut microbiome but also trigger the production of GLP-1 to regulate metabolic function. Which strains have this potential? Let’s review the list of ingredients.
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What ingredients are in each GLP-1 Probiotic serving?
Each GLP-1 Probiotic serving can be broken down into two components: the Probiotic Blend (500 million AFU) and the supporting ingredients. Starting with the Probiotic Blend of live strains, we have:
Clostridium butyricum (WB-STR-0006)
Clostridium butyricum (or C. butyricum) is described as a “butyrate-producing human gut symbiont,” meaning it is likely derived from human feces. It has been extensively studied with the digestive system in mind, seeing as it could positively impact the liver, adipose tissues, and brain function, among others. So far, studies have confirmed that this strain can modulate the gut microbiome, increasing the production of Bifidobacterium and Lactobacillus strains. Moreover, it has been shown to strengthen the gut barrier, protect mucin production, lower inflammation, and boost immune function.
Most of all, C. butyricum supplementation increased GLP-1 secretion from L-cells, improving metabolism. In terms of weight management, this ingredient might reduce weight gain and fat accumulation, improve insulin sensitivity, decrease fructosamine and G6Pase-supporting glucose metabolism, and increase markers of mitochondrial metabolism in the adipose tissue.
Akkermansia muciniphila (WB-STR-0001)
Akkermansia muciniphila (or A. muciniphila), like C. butyricum, is a human intestinal symbiont. Specifically, it is a mucin-degrading bacterium belonging to the Verrucomicrobia family. Regarding benefits, this ingredient is deemed imperative for increasing mucus thickness and maintaining gut barrier integrity. Moreover, researchers have generally linked A. muciniphila supplementation to restored mucus thickness, especially among those who are obese or have been diagnosed with type 2 diabetes.
A more recent study that looked at the effects of A. muciniphila on mice with the metabolic disease found that the strain triggered thermogenesis and GLP-1 secretion when paired with a high-fat diet. The reason for these results stems from the strain’s ability to secrete a protein called P9, which alone supposedly suffices to induce not only GLP-1 secretion but also brown adipose tissue (or good fat). Finally, a source referred to A. muciniphila as a “next-generation beneficial microbe,” given that it acts on various metabolic functions, including but not limited to energy balance, glucose metabolism, gut barrier, and endocrine functions.
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Bifidobacterium infantis
Bifidobacterium infantis (or B. infantis) is a lactic acid bacteria belonging to the family of Lactobacillus strains. It is naturally found in our oral cavity and gastrointestinal tract. One study that looked at the combined effects of probiotics and other ingredients on metabolic health stressed the importance of Bifidobacterium and Lactobacillus strains. In particular, the researchers insist that the duo produce lactate and acetate, which are then converted into butyrate. The latter plays significant roles in gastrointestinal inflammation, suppressing nuclear factor kappa B signaling, increasing GLP-1 release, and consequently, maintaining glucose balance, appetite control, and healthy inflammation levels.
The other component includes a single ingredient, as seen below:
Chicory Inulin (211 mg)
Chicory root comes from a plant belonging to the dandelion family of plants. The fiber from its root has since been attributed to several health benefits. For instance, it contains a prebiotic called inulin, which serves as fuel for probiotics. Second, it has been demonstrated to promote healthy digestion (by relieving constipation, softening stool, and increasing regularity). Since inulin stimulates probiotic development in the gut, individuals can anticipate improved insulin sensitivity and blood sugar levels. Some studies suggest inulin as a useful ingredient for weight loss due to its ability to regulate appetite and decrease caloric intake.
How much does the GLP-1 Probiotic cost?
Each GLP-1 Probiotic bottle includes a month’s worth of supply. With that, individuals have two options: one-time purchases or membership pricing. The latter is a subscription-based program where bottles are delivered automatically every 30, 90, or 180 days. Below are the different price options:
- 1 GLP-1 Probiotic bottle: $95 each, or subscribe for $65 each
- 3 GLP-1 Probiotic bottles: subscribe for $61.65 each
- 6 GLP-1 Probiotic bottles: subscribe for $58.50 each
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Meet Pendulum®
Pendulum consists of a team of scientists, doctors, and innovators who are all inspired by keeping one another healthy, happy, and well. Considering the team’s extensive background in biostatistics, microbiology, biotechnology, and medical research, it doesn’t surprise us that they are passionate about finding revolutionary, safe, and effective solutions. Regarding health, Pendulum understands that the solution to most health concerns rests in understanding the microbiome, and this is exactly what they aim to do daily. Of course, they aren’t venturing through this space on their own.
As much as the co-CEOs have a rich background, all products undergo consultation from Pendulum’s medical advisory board, scientific advisory board, and board of directors. With that, here are a few words from the team on why they decided to launch the GLP-1 Probiotic:
“At Pendulum, customers are the center of everything we do. We recognized there was a need for a natural solution to address cravings and appetite control, and our consumer studies and published research show that the beneficial bacteria strains used by Pendulum are particularly effective in this area.”
To learn more about each Pendulum team member’s role, visit the official website.
Frequently Asked Questions (FAQ)
Q: I’ve heard of CFU, but what is AFU in probiotics?
A: AFU stands for Active Fluorescent Units, meaning that each serving contains live, active bacteria, offering far more benefits than conventional supplements that fail to ensure their survival. CFU, or colony-forming unit, has been the industry standard for measuring strains; however, it doesn’t come close to AFU, seeing as AFU is more accurate.
Q: Is the GLP-1 Probiotic safe?
A: According to the Pendulum team, the GLP-1 Probiotic formula largely comprises commensal strains derived from the human gut. These strains, completely different from conventional probiotic supplements, have been repeatedly subjected to safety studies and have been found to be safe overall. If individuals have any questions or concerns, they should be directed to customer support, a healthcare provider, or both.
Q: Who should avoid taking the GLP-1 Probiotic?
A: Since the GLP-1 Probiotic has not been studied in women who are either pregnant, planning to become pregnant, or breastfeeding, individuals may want to consult with their respective healthcare providers to see whether it is a good fit. The same might hold for people with an existing medical condition warranting medication use.
Q: Are there side effects to taking the GLP-1 Probiotic?
A: There will definitely be a grace period to be mindful of. When just getting started, individuals might experience increased gas, bloating, nausea, or looseness in their stools. These initial symptoms should disappear within the first 14 days. If not, individuals are strongly advised to discontinue the supplement and seek immediate medical attention if needed.
Q: Was the GLP-1 Probiotic subjected to any studies?
A: The GLP-1 Probiotic has undergone a consumer study of 274 people taking the supplement. After 6 weeks, 91% of participants reported a reduction in food cravings. Given these promising results, the Pendulum team plans to conduct additional clinical trials to gain scientific insight into human probiotics’ effects on overall wellness.
Q: How do I take the GLP-1 Probiotic?
A: To get the most out of the GLP-1 Probiotic, individuals are recommended to take one capsule per day with food. According to the team, food reduces the amount of acid in the stomach and ensures that the capsule’s contents make it past the stomach. Otherwise, none of the targeted probiotics will reach their final destination.
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Q: Should I make lifestyle changes to incorporate the GLP-1 Probiotic?
A: Of course, a supplement on its own can only go so far. The Pendulum team strongly encourages taking each serving with a diet that is filled with colorful fruits, vegetables, polyphenols, and dietary fibers. Moreover, individuals might want to consider measures that help keep stress levels in check while also maintaining their physical health.
Q: What types of results can I expect from the GLP-1 Probiotic?
A: In the first 3 weeks of taking the GLP-1 Probiotic, individuals should notice mild digestive changes. This indicates that the strains are trying to find solace in their new environment. By the two-month mark, individuals should begin to feel some benefits. But it normally takes about three months to feel the full benefits, including a happy and healthy gut microbiome, a better mood, a healthy weight, and overall wellness.
Q: Will results slow over time while on the GLP-1 Probiotic?
A: Since the GLP-1 Probiotic has been designed to optimize GLP-1 levels in the body, there shouldn’t be that much of a plateau. The results should be reasonably consistent as long as individuals are on this supplement. Undoubtedly, lifestyle makes a dramatic difference in the significance of the results.
Q: Can I purchase the GLP-1 Probiotic using my HSA/FSA funds?
A: Yes, individuals can use their HSA/FDA funds. At checkout, there should be an option to get reimbursed after purchasing both memberships and one-time purchases.
Q: When can I expect my GLP-1 Probiotic order to arrive?
A: Orders to the contiguous United States and Canada will take anywhere between 4 and 5 business days from the time of purchase to arrive. Once orders have been shipped, individuals should receive their respective tracking numbers to follow progress.
Q: Does a money-back guarantee protect the GLP-1 Probiotic?
A: The GLP-1 Probiotic is protected by a 90-day money-back guarantee. If, within the first 90 days of taking this supplement, individuals see or feel no difference, customer service must be contacted to determine whether refunds are an option. The best way to do this is to submit a ticket online.
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Final Verdict
The GLP-1 Probiotic is a live-strain supplement designed to increase the production of the GLP-1 hormone in the body naturally. In so doing, individuals can anticipate suppressed appetite, better control over their caloric intakes and expenditures, blood sugar management, and, with time, healthy weight loss results. Certain probiotics have been shown to increase the production of certain short-chain fatty acids, which are critical for accelerating GLP-1 in the body. What makes Pendulum’s rendition of probiotic supplements unique is that they’ve resorted to strains found in the human gut and, quite literally, extracted from their feces. Although it might sound unappetizing, this strategy has recently emerged in this space and has repeatedly proven safe and effective.
Another facet that puts the GLP-1 Probiotic on the map is the simplistic nature of the formula itself. The creators focused on the fewest possible strains that have been clinically proven effective for current purposes. That’s not all; they ensured that each serving contained live strains. What’s the point otherwise? If strains are not live when they make it to the gastrointestinal tract and through the small intestine, we are only taking in meaningless fillers. Our editorial team has grown to respect the Pendulum team’s continued efforts to shed light on science and actively research an ever-changing and growing space.
The fact that we were able to navigate their strategy, understand it from start to finish, and fully see the potential that the GLP-1 Probiotic might have is not something we’ve seen in others. Coupled with their comprehensive guides, stringent board of directors, medical advisory board, and scientific advisory board, Pendulum’s GLP-1 Probiotic screams promise. To see whether you are fit for the GLP-1 Probiotic, visit the official website to learn more.
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